Hyperoxemia and long-term outcome after traumatic brain injury

Table 3 Adjusted outcomes by multivariable logistic regression model showing relationship between PaO ₂ groups and outcome

Variable	Odds ratio (95% CI)	P-value
	6-month mortality
Hypoxemia versus normoxemia	0.90 (0.57, 1.41)	0.648
Hyperoxemia versus normoxemia	0.88 (0.63, 1.22)	0.429
Hyperoxemia versus hypoxemia	0.97 (0.63, 1.50)	0.898
	In-hospital mortality
Hypoxemia versus normoxemia	1.01 (0.63, 1.62)	0.967
Hyperoxemia versus normoxemia	0.94 (0.65, 1.36)	0.753
Hyperoxemia versus hypoxemia	0.93 (0.59, 1.47)	0.766

Multivariate analysis adjusted for acute physiology and chronic health evaluation II (APACHE II) index independent of oxygenation (AP2no-ox), admission year (before or after 2007), emergency operation, intracranial pressure monitoring, controlled hypothermia and platelet count. PaO₂ (arterial oxygen tension) groups: hypoxemia, <10.0 kPa; normoxemia, 10.0 to 13.3 kPa; hyperoxemia, >13.3 kPa. The multivariable model displayed excellent discrimination (area under the curve 0.82, 0.83) and calibration (R_L² = 0.708, 0, 119) for predicting 6-month mortality and in-hospital mortality, respectively.

ISSN: 1364-8535