A protocol for resuscitation of severe burn patients guided by transpulmonary thermodilution and lactate levels: a 3-year prospective cohort study

Table 2 Hemodynamic, temperature and blood gas measurements

	Initial	24 hours	48 hours	72 hours
HR (bpm)	83 ± 21	95 ± 19	95 ± 19	95 ± 18
Temperature (°C)	35.5 ± 1.8	36.9 ± 1.0	36.6 ± 0.9	36.6 ± 1.3
MAP (mmHg)	85 ± 18	83 ± 13	79 ± 12	78 ± 8
PaO2/FiO2 ratio	338 ± 197	294 ± 114	269 ± 103	292 ± 136
CI (L/min/m²)	2.68 ± 1.06	3.22 ± 1.12	3.97 ± 1.12	4.43 ± 0.87
SVI (mL/m²)	33.7 ± 13.9	35.1 ± 13.2	42.7 ± 12.6	47.1 ± 10.7
ITBVI (mL/m²⁾	709 ± 254	744 ± 276	823 ± 230	896 ± 214
EVLWI (ml/kg)	6.97 ± 2.56	8.43 ± 4.52	8.85 ± 4.53	8.45 ± 3.80
SVCO₂ (%)	71.4 ± 8.5	72.5 ± 9.6	75.7 ± 8.7	73.9 ± 8.8
Base deficit	-3.5 ± 4.4	-0.9 ± 3.1	0.9 ± 2.3	2.2 ± 2.7
Arterial blood lactate (mmol/L)	2.58 ± 2.05	2.45 ± 1.78	1.87 ± 1.27	1.46 ± 1.02
Cardiac Troponin-I (ng/mL)	0.14 ± 0.59	0.16 ± 0.45	0.09 ± 0.27	0.07 ± 0.17
NTproBNP (pg/mL)	116 ± 387	280 ± 721	434 ± 961	482 ± 596
IAP (mm Hg)	9.7 ± 4.1	12.1 ± 8.2	11.1 ± 5.3	10.0 ± 3.0
EVLW/ITBV	0.38	0.35	0.31	0.28

bpm, beats/minute; CI, cardiac index; EVLWI, extravascular lung water volume index; HR, heart rate; IAP, intra-abdominal pressure; ITBVI, intrathoracic blood volume index; MAP, mean arterial pressure; NTproBNP, N-terminal pro-brain natriuretic peptide; SVCO₂, central venous oxygen saturation; SVI, indexed stroke volume.

ISSN: 1364-8535