Mean difference (CI) | P(mean) | Max difference (CI) | P(max) | ||
---|---|---|---|---|---|
HR (bpm) | C vs H | 12.7(-1.7 to 27.2) | NS(0.081) | 18.4(-1.3 to 38.2) | NS(0.066) |
C vs E | 16.3(2.0 to 30.5) | 0.027 | 25.6(6.0 to 45.2) | 0.013 | |
H vs E | 3.5(-10.6 to 17.7) | NS(0.609) | N/A | NS(0.151) | |
MAP (mmHg) | C vs H | -34.0(-44.7 to -23.3) | <0.001 | -48.6(-61.4 to -35.8) | <0.001 |
C vs E | -9.8(-20.6 to 1.1) | NS(0.075) | -29.9(-42.8 to -17.0) | <0.001 | |
H vs E | 24.3(14.2 to 34.3) | <0.001 | 29.1(16.6 to 41.6) | <0.001 | |
MPAP (mmHg) | C vs H | -3.5(-7.0 to -0.1) | 0.047 | unable to identify sig. changes | NS(0.107) |
C vs E | 10.9(7.2 to 14.7) | <0.001 | 19.4(14.4 to 24.4) | <0.001 | |
H vs E | 14.5(10.8 to 18.1) | <0.001 | 23.3(18.4 to 28.1) | <0.001 | |
CVP (mmHg) | C vs H | -1.8(-3.4 to -0.2) | 0.029 | -2.4(-4.3 to -0.4) | 0.020 |
C vs E | -0.3(-1.8 to 1.3) | NS(0.722) | N/A | NS(0.295) | |
H vs E | 1.5(0.1 to 3.0) | 0.041 | 2.9(1.0 to 4.7) | 0.004 | |
PCWP (mmHg) | C vs H | -2.4(-4.0 to -0.9) | 0.004 | -3.0(-5.0 to -0.9) | 0.008 |
C vs E | 0.5(-1.0 to 2.1) | NS(0.464) | 2.9(0.9 to 5.0) | 0.007 | |
H vs E | 3.0(1.5 to 4.4) | <0.001 | 5.1(3.2 to 7.1) | <0.001 | |
SVI (ml/m2) | C vs H | -8.2(-12.5 to -3.8) | 0.001 | -10.5(-16.6 to -4.5) | 0.002 |
C vs E | -6.0(-10.3 to -1.7) | 0.008 | -7.8(-13.8 to -1.7) | 0.014 | |
H vs E | 2.1(-2.3 to 6.5) | NS(0.322) | 5.4(-0.6 to 11.4) | NS(0.076) | |
SmvO2 (%) | C vs H | -23.8(-32.9 to -14.7) | <0.001 | -33.4(-45.4 to -21.4) | <0.001 |
C vs E | -6.1(-15.2 to 3.0) | NS(0.178) | -14.9(-26.9 to -2.9) | 0.017 | |
H vs E | 17.7(9.2 to 26.2) | <0.001 | 19.2(8.0 to 30.4) | 0.002 | |
A-Lac (mmol/L) | C vs H | 2.3(0.6 to 4.1) | 0.011 | 2.7(0.7 to 4.7) | 0.010 |
C vs E | 2.8(1.0 to 4.6) | 0.003 | 3.3(1.3 to 5.3) | 0.003 | |
H vs E | 0.5(-1.1 to 2.1) | NS(0.529) | N/A | NS(0.188) | |
DO2i (ml/min/m2) | C vs H | -96.2(-157.2 to -35.2) | 0.004 | -113.6(-185.7 to -41.5) | 0.004 |
C vs E | 1.6(-61.5 to 64.6) | NS(0.959) | N/A | NS(0.536) | |
H vs E | 97.8(35.5 to 160.0) | 0.004 | 120.1(47.0 to 193.1) | 0.003 | |
VO2i (ml/min/m2) | C vs H | 0.7(-28.8 to 30.2) | NS(0.962) | N/A | NS(0.275) |
C vs E | 14.8(-17.0 to 46.6) | NS(0.343) | N/A | NS(0.242) | |
H vs E | 14.1(-16.6 to 44.8) | NS(0.349) | N/A | NS(0.210) | |
O2ER | C vs H | 0.2 (0.2 to 0.3) | <0.001 | 0.3(0.2 to 0.4) | <0.001 |
C vs E | 0.1(0.0 to 0.2) | NS(0.119) | 0.1(0.0 to 0.2) | 0.029 | |
H vs E | -0.2(-0.3 to -0.1) | <0.001 | -0.2(-0.1 to -0.3) | 0.001 | |
LVSWI (g.mm2) | C vs H | -16.9(-22.6 to -11.2) | <0.001 | -24.4(-31.4 to -17.3) | <0.001 |
C vs E | -9.1(-14.7 to -3.6) | 0.003 | -17.2(-24.2 to -10.3) | <0.001 | |
H vs E | 7.8(2.3 to 13.3) | 0.008 | 9.5(2.3 to 16.7) | 0.012 | |
RVSWI (g.mm2) | C vs H | -2.2(-4.0 to -0.5) | 0.016 | -2.6(-4.9 to -0.3) | 0.031 |
C vs E | 2.0(0.2 to 3.8) | 0.027 | 4.9(2.6 to 7.2) | <0.001 | |
H vs E | 4.2(2.5 to 6.0) | <0.001 | 7.5(5.2 to 9.7) | <0.001 | |
EF (%) | C vs H | 2.9(-1.8 to 7.5) | NS(0.210) | N/A | NS(0.263) |
C vs E | -9.5(-14.4 to -4.7) | 0.001 | -10.5(-16.6 to -4.5) | 0.002 | |
H vs E | -12.4(-17.0 to -7.8) | <0.001 | -13.1(-18.9 to -7.4) | <0.001 | |
TDI (mm) | C vs H | -0.5(-1.1 to 0.2) | NS(0.143) | -1.0(-2.1 to 0.0) | NS(0.055) |
C vs E | -0.4(-1.1 to 0.2) | NS(0.182) | -1.0(-2.2 to 0.2) | NS(0.092) | |
H vs E | 0.0(-0.6 to 0.7) | NS(0.943) | N/A | NS(0.462) | |
VTI (cm) | C vs H | -4.0(-6.3 to -1.8) | 0.001 | -5.7(-8.4 to -3.1) | <0.001 |
C vs E | -2.2(-4.5 to 0.1) | NS(0.056) | -2.8(-5.6 to 0.0) | 0.048 | |
H vs E | 1.8(-0.4 to 4.0) | NS(0.099) | 3.8(1.3 to 6.3) | 0.005 | |
TAPSE (mm) | C vs H | -1.2(-3.5 to 1.0) | 0.268 | -2.7(-5.5 to 0.1) | NS(0.060) |
C vs E | -3.0(-5.1 to -0.9) | 0.008 | -4.0(-6.7 to -1.3) | 0.006 | |
H vs E | -1.8(-3.9 to 0.4) | NS(0.105) | -3.3(-5.9 to -0.6) | 0.018 | |
TR (mmHg) | C vs H | -1.7(-10.7 to 7.3) | NS(0.695) | N/A | NS(0.441) |
C vs E | 8.3(-0.8 to 17.4) | NS(0.070) | 10.3(-0.4 to 21.1) | NS(0.059) | |
H vs E | 10.0(2.0 to 18.1) | 0.018 | 14.5(5.0 to 24.0) | 0.005 | |
E/A | C vs H | 0.1(-0.2 to 0.4) | NS(0.491) | N/A | NS(0.098) |
C vs E | -0.3(-0.7 to 0.0) | 0.034 | -0.5(-0.8 to -0.1) | 0.015 | |
H vs E | -0.5(-0.8 to -0.2) | 0.005 | -0.6(-1.0 to -0.2) | 0.004 | |
E/é | C vs H | 2.5(0 to 5.1) | 0.051 | 4.0(0.3 to 7.7) | 0.036 |
C vs E | -1.5(-4.1 to 1.1) | NS(0.236) | N/A | NS(0.066) | |
H vs E | -4.0(-1.6 to -6.5) | 0.002 | -5.5(-8.9 to -2.1) | 0.003 |