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Table 1 Baseline characteristics of patients with ALI/ARDS or CPE

From: Increased plasma levels of heparin-binding protein in patients with acute respiratory distress syndrome

Characteristic ALI/ARDS (n= 78) CPE (n= 28) Pvalue
Demographics    
  Age (years) 63 (54 to 68) 66 (58 to 72) 0.231
  Male 45 (57.7) 15 (53.6) 0.706
  Body mass index (kg/m2) 23 (19 to 26) 23 (18 to 26) 0.297
Comorbidities    
  Post operation 16 (20.5) 4 (14.3) 0.659
  Atrial fibrillation 5 (6.4) 6 (21.4) 0.025*
  Coronary artery disease 13 (16.7) 7 (25.0) 0.334
  Chronic obstructive pulmonary disease 14 (17.9) 3 (10.7) 0.552
  Hypertension 22 (28.2) 6 (21.4) 0.485
  Diabetes 20 (25.6) 5 (17.9) 0.405
  Chronic kidney disease 8 (10.3) 2 (7.1) 0.915
  APACHE II score 18 (14 to 22) 15 (13 to 18) 0.067
  SOFA score 8 (5 to 10) 4 (3 to 7) 0.037*
Ventilatory data    
  Mechanical ventilation 49 (62.8) 15 (53.6) 0.391
  Arterial pH 7.36 (7.31 to 7.42) 7.41 (7.37 to 7.48) 0.398
  Arterial lactate 1.8 (1.1 to 2.3) 1.5 (1.2 to 1.9) 0.165
  PO2/FiO2 166 (132 to 202) 224 (176 to 268) 0.033*
Echocardiography    
  Patients examined 65 (83.3) 25 (89.3) 0.450
  LVEF (%) 55 (51 to 61) 48 (41 to 53) 0.038*
Hemodynamics    
  Patients examined 31 (39.7) 12 (42.9) 0.773
  PAOP (mmHg) 14 (9 to 16) 23 (21 to 25) 0.042*
  Cardiac index (l/min/m2) 3.01 (2.55 to 3.18) 2.85 (2.56 to 3.12) 0.671
  SvO2 (%) 61 (53 to 66) 67 (60 to 73) 0.091
Laboratory findings    
  White blood cell (109/l) 12.1 (8.6 to 14.8) 9.3 (6.3 to 12.5) 0.315
  Platelet (109/l) 182 (137 to 255) 191 (155 to 257) 0.871
  APTT (seconds) 30 (24 to 37) 31 (26 to 35) 0.672
  Bilirubin (μmol/l) 11.7 (7.2 to 16.8) 9.1 (6.8 to 13.9) 0.774
  Glucose (mmol/l) 6.7 (5.2 to 7.0) 6.5 (5.3 to 6.9) 0.781
  Albumin (g/l) 28.2 (26.1 to 30.6) 30.2 (26.1 to 33.8) 0.317
  Creatinine (μmol/l) 71 (55 to 88) 76 (55 to 91) 0.225
  HBP (ng/ml) 17.15 (11.95 to 24.07) 9.50 (7.98 to 12.18) <0.001*
  Length of ICU stay (days) 9 (5 to 15) 7 (4 to 12) 0.221
  1. Data presented as median (interquartile range) for continuous variables and number (%) for categorical variables. ALI, acute lung injury; APACHE, Acute Physiology and Chronic Health Evaluation; APTT, activated partial thromboplastin time; ARDS, acute respiratory distress syndrome; CPE, cardiogenic pulmonary edema; HBP, heparin-binding protein; LVEF, left ventricular ejection fraction; PAOP, pulmonary artery occlusion pressure; PO2/FiO2, ratio of arterial oxygen partial pressure and inspiratory oxygen fraction; SOFA, Sequential Organ Failure Assessment; SvO2, oxygen saturation of venous blood. *P <0.05.