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Table 4 Comparisons of baseline characteristics between survivors and non-survivors.

From: Etiologies, diagnostic strategies, and outcomes of diffuse pulmonary infiltrates causing acute respiratory failure in cancer patients: a retrospective observational study

 

Survivor (n= 109, 51%)

Non-survivor (n= 105, 49%)

Odds ratio (95% CI)

P value

Age (years)

59 (51-66)

62 (51-69)

1.007 (0.998-1.027)

0.477

Gender (male)

71/144 (49)

73/144 (51)

1.221 (0.689-2.165)

0.494

Co-morbidity

51/111 (46)

60/111 (54)

1.516 (0.884-2.600)

0.130

Type of malignancy

    

   Hematology

60/115 (52)

55/115 (48)

0.898 (0.525-1.538)

0.696

ECOG performance status (3 or more)

22/61 (36)

39/61 (64)

2.337 (1.266-4.313)

0.006

Status of malignancy

    

   Relapsed/refractory

24/64 (38)

40/64 (63)

2.179 (1.196-3.973)

0.010

   Extensive or major organ involvement

76/151 (50)

75/151 (50)

1.086 (0.603-1.955)

0.785

   Stem cell transplantation

9/28 (32)

19/28 (68)

2.455 (1.056-5.708)

0.033

   Duration of malignancy, months

9.8 (3.1-22.5)

6.9 (2.7-18.4)

0.997 (0.989-1.005)

0.486

Clinical status on ICU admission

    

   Recent chemotherapy

88/182 (48)

94/182 (52)

2.039 (0.930-4.472)

0.071

   Need for mechanical ventilationa

44/109 (40)

65.109 (60)

2.401 (1.386-4.157)

0.002

   Need for vasopressor support

20/52 (39)

32/52 (62)

1.951 (1.030-3.695)

0.039

   Need for renal replacement therapy

8/19 (42)

11/19 (58)

1.477 (0.570-3.832)

0.42

Neutropenia

12/40 (30)

28/40 (70)

2.939 (1.403-6.157)

0.003

Severity of illness

    

   SAPS 3 (points)

59 (50-72)

64 (50-76)

1.016 (1.001 - 1.032)

0.0420

   SOFA score (points)

5 (3-7)

7 (4-9)

1.125 (1.033 - 1.226)

0.007

Identified etiology

96/187 (51)

91/187 (49)

0.880 (0.393 - 1.974)

0.757

Therapeutic modification

61/99 (62)

38/99 (38)

0.446 (0.258 - 0.773)

0.004

  1. aNumber includes both invasive and non-invasive mechanical ventilation.
  2. CI, confidence interval; ECOG, Eastern Cooperative Oncology Group; ICU, intensive care unit; SAPS 3, Simplified Acute Physiology Score 3; SOFA, Sequential Organ Failure Assessment.