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Table 3 The factors associated with 6-month mortality in patients with aneurysmal subarachnoid hemorrhage.

From: Plasma gelsolin levels and outcomes after aneurysmal subarachnoid hemorrhage

 

Non-survival group (n= 31)

Survival group (n= 231)

Univariate analysis P value

Sex (male/female)

13/18

99/132

0.922

Age (years)

44.4 ± 12.0

43.5 ± 12.2

0.695

WFNS score on admission

4 (1)

2 (2)

< 0.001

Fisher score on admission

4 (1)

2 (1)

< 0.001

Aneurysmal location

  

0.974

   Posterior communication artery

7 (22.6%)

71 (30.7%)

 

   Internal carotid artery

6 (19.4%)

34 (14.7%)

 

   Anterior communication artery

7 (22.6%)

52 (22.5%)

 

   Middle cerebral artery

5 (16.1%)

34 (14.7%)

 

   Anterior cerebral artery

4 (12.9%)

26 (11.3%)

 

   Posterior cerebral artery

1 (3.2%)

9 (3.9%)

 

   Vertebral artery

1 (3.2%)

5 (2.2%)

 

Surgery

20 (64.5%)

143 (61.9%)

0.778

Acute hydrocephalus

20 (64.5%)

59 (34.2%)

< 0.001

Intraventricular hemorrhage

27 (87.1%)

28 (12.1%)

< 0.001

External ventricular drain

28 (90.3%)

63 (27.3%)

< 0.001

Vasospasm

28 (90.3%)

84 (36.4%)

< 0.001

CT ischemia

12 (38.7%)

27 (11.7%)

< 0.001

Admission time (h)

4.0 (6.0)

4.0 (4.0)

0.826.

Plasma-sampling time (h)

6.0 (7.4)

5.4 (6.4)

0.398

Seizure

7 (22.5%)

30 (13.0%)

0.174

Systolic arterial pressure (mmHg)

130 (36)

130 (30)

0.373

Diastolic arterial pressure (mmHg)

81 (21)

80 (22)

0.421

Mean arterial pressure (mmHg)

101 (23)

97 (25)

0.257

Heart rate (beats/min)

81 (23)

80 (36)

0.602

Body temperature (°C)

36.7 (1.9)

36.5 (0.9)

0.551

Respiratory rate (respirations/min)

19 (3)

18 (5)

0.935

Blood oxygen saturation (%)

88 (7)

88 (5)

0.344

Blood white blood cell count (×109/L)

6.5 (6.1)

7.5 (4.0)

0.566

Blood hemoglobin level (g/L)

122 (37)

125 (37)

0.129

Blood platelet count (×109/L)

183 (34)

173 (56)

0.269

Blood glucose level (mmol/L)

10.7 (5.9)

9.1 (2.6)

0.003

Blood sodium level (mmol/L)

135 (11)

136 (7)

0.673

Blood potassium level (mmol/L)

3.8 (1.3)

3.7 (0.9)

0.926

Prothrombin time (s)

14.5 (3.2)

14.6 (4.1)

0.659

Thrombin time (s)

18.4 ± 2.9

18.9 ± 3.3

0.369

Partial thromboplastin time (s)

39.5 (11.8)

39.4 (10.6)

0.476

Plasma C-reactive protein level (mg/L)

8.1 (6.5)

6.2 (3.6)

0.013

Plasma fibrinogen level (g/L)

4.8 (4.2)

3.9 (3.8)

0.036

Plasma D-dimer level (mg/L)

2.3 (1.2)

1.8 (1.1)

0.014

Plasma gelsolin level (mg/L)

49.0 (17.9)

70.3 (25.5)

< 0.001

  1. Numerical variables were presented as median (interquartile range) or mean ± standard deviation. Categorical variables were expressed as counts (percentage). Numerical variables were analyzed by Mann-Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test.
  2. n, number of patients; WFNS, World Federation of Neurological Surgeons.