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Table 3 The factors associated with 6-month mortality in patients with aneurysmal subarachnoid hemorrhage.

From: Plasma gelsolin levels and outcomes after aneurysmal subarachnoid hemorrhage

  Non-survival group (n= 31) Survival group (n= 231) Univariate analysis P value
Sex (male/female) 13/18 99/132 0.922
Age (years) 44.4 ± 12.0 43.5 ± 12.2 0.695
WFNS score on admission 4 (1) 2 (2) < 0.001
Fisher score on admission 4 (1) 2 (1) < 0.001
Aneurysmal location    0.974
   Posterior communication artery 7 (22.6%) 71 (30.7%)  
   Internal carotid artery 6 (19.4%) 34 (14.7%)  
   Anterior communication artery 7 (22.6%) 52 (22.5%)  
   Middle cerebral artery 5 (16.1%) 34 (14.7%)  
   Anterior cerebral artery 4 (12.9%) 26 (11.3%)  
   Posterior cerebral artery 1 (3.2%) 9 (3.9%)  
   Vertebral artery 1 (3.2%) 5 (2.2%)  
Surgery 20 (64.5%) 143 (61.9%) 0.778
Acute hydrocephalus 20 (64.5%) 59 (34.2%) < 0.001
Intraventricular hemorrhage 27 (87.1%) 28 (12.1%) < 0.001
External ventricular drain 28 (90.3%) 63 (27.3%) < 0.001
Vasospasm 28 (90.3%) 84 (36.4%) < 0.001
CT ischemia 12 (38.7%) 27 (11.7%) < 0.001
Admission time (h) 4.0 (6.0) 4.0 (4.0) 0.826.
Plasma-sampling time (h) 6.0 (7.4) 5.4 (6.4) 0.398
Seizure 7 (22.5%) 30 (13.0%) 0.174
Systolic arterial pressure (mmHg) 130 (36) 130 (30) 0.373
Diastolic arterial pressure (mmHg) 81 (21) 80 (22) 0.421
Mean arterial pressure (mmHg) 101 (23) 97 (25) 0.257
Heart rate (beats/min) 81 (23) 80 (36) 0.602
Body temperature (°C) 36.7 (1.9) 36.5 (0.9) 0.551
Respiratory rate (respirations/min) 19 (3) 18 (5) 0.935
Blood oxygen saturation (%) 88 (7) 88 (5) 0.344
Blood white blood cell count (×109/L) 6.5 (6.1) 7.5 (4.0) 0.566
Blood hemoglobin level (g/L) 122 (37) 125 (37) 0.129
Blood platelet count (×109/L) 183 (34) 173 (56) 0.269
Blood glucose level (mmol/L) 10.7 (5.9) 9.1 (2.6) 0.003
Blood sodium level (mmol/L) 135 (11) 136 (7) 0.673
Blood potassium level (mmol/L) 3.8 (1.3) 3.7 (0.9) 0.926
Prothrombin time (s) 14.5 (3.2) 14.6 (4.1) 0.659
Thrombin time (s) 18.4 ± 2.9 18.9 ± 3.3 0.369
Partial thromboplastin time (s) 39.5 (11.8) 39.4 (10.6) 0.476
Plasma C-reactive protein level (mg/L) 8.1 (6.5) 6.2 (3.6) 0.013
Plasma fibrinogen level (g/L) 4.8 (4.2) 3.9 (3.8) 0.036
Plasma D-dimer level (mg/L) 2.3 (1.2) 1.8 (1.1) 0.014
Plasma gelsolin level (mg/L) 49.0 (17.9) 70.3 (25.5) < 0.001
  1. Numerical variables were presented as median (interquartile range) or mean ± standard deviation. Categorical variables were expressed as counts (percentage). Numerical variables were analyzed by Mann-Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test.
  2. n, number of patients; WFNS, World Federation of Neurological Surgeons.