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Table 2 The factors associated with 6-month function outcome in patients with aneurysmal subarachnoid hemorrhage.

From: Plasma gelsolin levels and outcomes after aneurysmal subarachnoid hemorrhage

 

GOS 1-3 (n= 73)

GOS 4-5 (n= 189)

Univariate analysis P value

Sex (male/female)

34/39

78/111

0.463

Age (years)

44.5 ± 10.5

43.2 ± 12.7

0.847

WFNS score on admission

3 (1)

2 (2)

< 0.001

Fisher score on admission

4 (1)

2 (1)

< 0.001

Aneurysmal location

  

0.761

   Posterior communication artery

27 (37.0%)

51 (27.0%)

 

   Internal carotid artery

11 (15.1%)

29(15.3%)

 

   Anterior communication artery

15 (20.5%)

44 (23.3%)

 

   Middle cerebral artery

10 (13.7%)

29 (15.3%)

 

   Anterior cerebral artery

6 (8.2%)

24 (12.7%)

 

   Posterior cerebral artery

2 (2.7%)

8 (4.2%)

 

   Vertebral artery

2 (2.7%)

4 (2.1%)

 

Surgery

46 (63.0%)

117 (61.9%)

0.868

Acute hydrocephalus

39 (53.4%)

40 (21.2%)

< 0.001

Intraventricular hemorrhage

44 (60.3%)

11 (5.8%)

< 0.001

External ventricular drain

51 (69.9%)

40 (21.2%)

< 0.001

Vasospasm

56 (76.7%)

56 (29.6%)

< 0.001

CT ischemia

20 (27.4%)

19 (10.1%)

< 0.001

Admission time (h)

4.0 (3.5)

4.0 (4.7)

0.259

Plasma-sampling time (h)

5.4 (5.6)

5.6 (6.6)

0.204

Seizure

14 (19.2%)

23 (12.2%)

0.144

Systolic arterial pressure (mmHg)

129 (34)

131 (30)

0.748

Diastolic arterial pressure (mmHg)

79 (18)

81 (24)

0.706

Mean arterial pressure (mmHg)

98 (20)

97 (25)

0.530

Heart rate (beats/min)

81 (34)

79 (35)

0.716

Body temperature (°C)

36.4 (1.6)

36.5 (0.9)

0.381

Respiratory rate (respirations/min)

19 (3)

18 (4)

0.150

Blood oxygen saturation (%)

88 (5)

89 (5)

0.795

Blood white blood cell count (×109/L)

7.8 (5.8)

7.4 (3.7)

0.607

Blood hemoglobin level (g/L)

124 (36)

125 (39)

0.409

Blood platelet count (×109/L)

173 (43)

174 (56)

0.863

Blood glucose level (mmol/L)

10.4 (4.6)

8.9 (2.4)

< 0.001

Blood sodium level (mmol/L)

136 (8)

136 (8)

0.916

Blood potassium level (mmol/L)

3.7 (1.0)

3.7 (0.9)

0.904

Prothrombin time (s)

14.2 (4.0)

14.8 (4.1)

0.601

Thrombin time (s)

18.8 ± 3.2

18.9 ± 3.2

0.942

Partial thromboplastin time (s)

40.3 (11.2)

39.3 (10.8)

0.332

Plasma C-reactive protein level (mg/L)

8.0 (5.9)

6.1 (3.3)

< 0.001

Plasma fibrinogen level (g/L)

5.3 (4.4)

3.7 (3.2)

0.001

Plasma D-dimer level (mg/L)

2.1 (1.6)

1.7 (1.0)

0.003

Plasma gelsolin level (mg/L)

52.8 (17.5)

75.7 (22.6)

< 0.001

  1. Numerical variables were presented as median (interquartile range) or mean ± standard deviation. Categorical variables were expressed as counts (percentage). Numerical variables were analyzed by Mann-Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test.
  2. GOS, Glasgow outcome scale; n, number of patients; WFNS, World Federation of Neurological Surgeons.