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Table 2 The factors associated with 6-month function outcome in patients with aneurysmal subarachnoid hemorrhage.

From: Plasma gelsolin levels and outcomes after aneurysmal subarachnoid hemorrhage

  GOS 1-3 (n= 73) GOS 4-5 (n= 189) Univariate analysis P value
Sex (male/female) 34/39 78/111 0.463
Age (years) 44.5 ± 10.5 43.2 ± 12.7 0.847
WFNS score on admission 3 (1) 2 (2) < 0.001
Fisher score on admission 4 (1) 2 (1) < 0.001
Aneurysmal location    0.761
   Posterior communication artery 27 (37.0%) 51 (27.0%)  
   Internal carotid artery 11 (15.1%) 29(15.3%)  
   Anterior communication artery 15 (20.5%) 44 (23.3%)  
   Middle cerebral artery 10 (13.7%) 29 (15.3%)  
   Anterior cerebral artery 6 (8.2%) 24 (12.7%)  
   Posterior cerebral artery 2 (2.7%) 8 (4.2%)  
   Vertebral artery 2 (2.7%) 4 (2.1%)  
Surgery 46 (63.0%) 117 (61.9%) 0.868
Acute hydrocephalus 39 (53.4%) 40 (21.2%) < 0.001
Intraventricular hemorrhage 44 (60.3%) 11 (5.8%) < 0.001
External ventricular drain 51 (69.9%) 40 (21.2%) < 0.001
Vasospasm 56 (76.7%) 56 (29.6%) < 0.001
CT ischemia 20 (27.4%) 19 (10.1%) < 0.001
Admission time (h) 4.0 (3.5) 4.0 (4.7) 0.259
Plasma-sampling time (h) 5.4 (5.6) 5.6 (6.6) 0.204
Seizure 14 (19.2%) 23 (12.2%) 0.144
Systolic arterial pressure (mmHg) 129 (34) 131 (30) 0.748
Diastolic arterial pressure (mmHg) 79 (18) 81 (24) 0.706
Mean arterial pressure (mmHg) 98 (20) 97 (25) 0.530
Heart rate (beats/min) 81 (34) 79 (35) 0.716
Body temperature (°C) 36.4 (1.6) 36.5 (0.9) 0.381
Respiratory rate (respirations/min) 19 (3) 18 (4) 0.150
Blood oxygen saturation (%) 88 (5) 89 (5) 0.795
Blood white blood cell count (×109/L) 7.8 (5.8) 7.4 (3.7) 0.607
Blood hemoglobin level (g/L) 124 (36) 125 (39) 0.409
Blood platelet count (×109/L) 173 (43) 174 (56) 0.863
Blood glucose level (mmol/L) 10.4 (4.6) 8.9 (2.4) < 0.001
Blood sodium level (mmol/L) 136 (8) 136 (8) 0.916
Blood potassium level (mmol/L) 3.7 (1.0) 3.7 (0.9) 0.904
Prothrombin time (s) 14.2 (4.0) 14.8 (4.1) 0.601
Thrombin time (s) 18.8 ± 3.2 18.9 ± 3.2 0.942
Partial thromboplastin time (s) 40.3 (11.2) 39.3 (10.8) 0.332
Plasma C-reactive protein level (mg/L) 8.0 (5.9) 6.1 (3.3) < 0.001
Plasma fibrinogen level (g/L) 5.3 (4.4) 3.7 (3.2) 0.001
Plasma D-dimer level (mg/L) 2.1 (1.6) 1.7 (1.0) 0.003
Plasma gelsolin level (mg/L) 52.8 (17.5) 75.7 (22.6) < 0.001
  1. Numerical variables were presented as median (interquartile range) or mean ± standard deviation. Categorical variables were expressed as counts (percentage). Numerical variables were analyzed by Mann-Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test.
  2. GOS, Glasgow outcome scale; n, number of patients; WFNS, World Federation of Neurological Surgeons.