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Table 4 ESRD risk and adjusted HR between 181 days and five years after ICU by D-AKI status

From: Five-year risk of end-stage renal disease among intensive care patients surviving dialysis-requiring acute kidney injury: a nationwide cohort study

 

D-AKI

Other ICU patients

Adjusted HR (95% CI)a

 

Total

(n)

ESRD (n)

Cumulative risk % (95% CI)

Total

(n)

ESRD (n)

Cumulative risk % (95% CI)

 

Age, y

       

   15 to 49

484

14

3.4 (1.9 - 5.5)

30,299

38

0.18 (0.13 - 0.24)

12.8 (6.5 - 25.4)

   50 to 69

1,227

33

3.9 (2.6 - 5.4)

40,750

129

0.44 (0.37 - 0.53)

5.3 (3.6 - 8.0)

   ≥70

864

29

4.0 (2.7 - 5.7)

30,330

82

0.35 (0.28 - 0.43)

6.9 (4.4 - 10.9)

Gender

       

   Female

952

34

5.0 (3.2 - 7.5)

43,955

99

0.30 (0.24 - 0.37)

7.3 (4.8 - 11.1)

   Male

1,627

42

3.3 (2.3 - 4.6)

57,462

150

0.36 (0.30 - 0.42)

5.5 (3.9 - 8.0)

Chronic kidney disease

       

   Yes

218

28

18.4 (12.2 - 25.6)

1,795

102

7.23 (5.94 - 8.81)

2.8 (1.8 - 4.3)

   No

2,361

48

2.7 (2.0 - 3.6)

99,622

147

0.21 (0.18 - 0.25)

11.9 (8.5 - 16.8)

Diabetes

       

   Yes

434

29

10.3 (6.7 - 14.7)

8,232

83

1.51 (1.20 - 1.88)

6.0 (3.9 - 9.4)

   No

2,145

47

2.7 (2.0 - 3.6)

93,102

166

0.23 (0.20 - 0.27)

6.7 (4.7 - 9.4)

Surgical status

       

   No surgery

1,033

33

4.3 (2.9 - 6.1)

36,986

100

0.35 (0.28 - 0.42)

6.0 (4.0 - 9.2)

   Surgery

       

   Acute non-cardiac surgery

960

23

3.0 (1.9 - 4.5)

29,341

73

0.35 (0.27 - 0.44)

5.8 (3.5 - 9.5)

   Acute cardiac surgery

143

1

1.0 (0.1 - 5.9)

2,478

5

0.27 (0.10 - 0.62)

3.9 (0.4 - 39.9)

   Elective non-cardiac surgery

226

5

2.8 (1.0 - 6.1)

18,640

34

0.25 (0.17 - 0.36)

8.7 (3.2 - 23.3)

   Elective cardiac surgery

217

14

8.2 (4.6 - 13.2)

13,972

37

0.39 (0.28 - 0.54)

10.8 (5.3 - 22.3)

  1. aCompared to ICU patents not treated with dialysis within the same subgroup and adjusted for age group, gender, chronic kidney disease, diabetes, hypertension, congestive heart failure, myocardial infarction, peripheral vascular disease, cerebrovascular disease, cancer and surgical status.
  2. CI, confidence interval; D-AKI, dialysis requiring acute kidney injury; ESRD, end-stage renal disease; HR, hazard ratio; ICU, intensive care unit; n, number