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Table 1 Characteristics and survival of cancer patients categorized by duration of mechanical ventilation (1998 to 2007).a

From: Incidence, life expectancy and prognostic factors in cancer patients under prolonged mechanical ventilation: a nationwide analysis of 5,138 cases during 1998-2007

 

Duration of mechanical ventilation

 

>7 days (extended MV)

>21 days (prolonged MV)

Variables

N

Median survival, months (IQR)

1-yr survival rate, % (95% CI)

N

Median survival, months (IQR)

1-yr survival rate, % (95% CI)

Life expectancy, yr (SE)

Total

9,011

1.54 (0.67 to 5.90)

17.6 (16.8 to 18.4)

5138

1.37 (0.50 to 4.57)

14.3 (13.3 to 15.3)

1.21 (0.10)

Gender and age (yr)

       

Male

       

   17 to 64

2,282

1.64 (0.66 to 8.29)

20.4 (18.8 to 22.2)

1,010

1.17 (0.43 to 3.73)

13.9 (11.8 to 16.2)

1.52 (0.22)

   65 to 74

1,686

1.50 (0.67 to 5.10)

16.7 (14.9 to 18.5)

986

1.37 (0.50 to 4.23)

12.8 (10.8 to 15.1)

1.02 (0.13)

   75 to 84

1,729

1.50 (0.70 to 4.94)

15.1 (13.4 to 16.9)

1,116

1.40 (0.53 to 4.63)

13.3 (11.3 to 15.4)

0.86 (0.09)

   85 or older

425

1.64 (0.77 to 4.50)

14.9 (11.6 to 18.6)

318

1.80 (0.63 to 4.73)

16.4 (12.4 to 20.9)

0.95 (0.19)

Female

       

   17 to 64

1,129

1.40 (0.60 to 6.84)

19.8 (17.5 to 22.3)

573

1.30 (0.43 to 5.43)

17.2 (14.2 to 20.5)

1.49 (0.31)

   65 to 74

788

1.54 (0.64 to 5.27)

17.2 (14.6 to 20.0)

459

1.40 (0.63 to 4.53)

13.9 (10.9 to 17.3)

1.03 (0.24)

   75 to 84

727

1.50 (0.67 to 5.50)

14.3 (11.8 to 17.1)

499

1.47 (0.57 to 5.83)

14.8 (11.7 to 18.2)

1.07 (0.30)

   85 or older

234

1.84 (0.86 to 6.67)

17.6 (12.9 to 23.0)

177

1.70 (0.73 to 6.20)

16.4 (11.1 to 22.6)

0.82 (0.24)

Extent of cancer

       

   Local

5,954

1.87 (0.79 to 8.32)

20.6 (19.5 to 21.7)

3,900

1.60 (0.57 to 5.97)

16.9 (15.7 to 18.2)

1.36 (0.11)

   Metastasis

3,057

1.07 (0.50 to 3.12)

11.7 (10.6 to 12.9)

1,238

0.93 (0.37 to 2.10)

5.9 (4.6 to 7.3)

0.64 (0.15)

Cancer type

       

   Head and neck

1,432

2.60 (0.89 to 13.32)

26.0 (23.7 to 28.3)

705

1.77 (0.70 to 7.57)

20.0 (17.0 to 23.1)

1.57 (0.45)

   Bone and connective tissue

52

1.37 (0.77 to 2.74)

10.0 (3.7 to 20.1)

38

0.87 (0.37 to 1.77)

2.8 (2.1 to 12.2)

-b

   Liver

775

0.87 (0.40 to 2.50)

10.5 (8.4 to 12.8)

297

1.00 (0.40 to 2.43)

6.8 (4.2 to 10.2)

0.45 (0.19)

   Lung

1,752

1.10 (0.56 to 2.93)

10.5 (9.1 to 12.1)

965

1.00 (0.37 to 2.57)

6.6 (5.1 to 8.3)

0.77 (0.13)

   Esophagus

495

2.07 (0.86 to 9.17)

22.5 (18.8 to 26.3)

232

1.03 (0.47 to 2.83)

10.2 (6.6 to 14.6)

0.98 (0.33)

   Lymphatic and hematopoietic tissue

578

1.20 (0.57 to 4.47)

14.2 (11.5 to 17.2)

289

1.27 (0.43 to 4.33)

14.3 (10.4 to 18.7)

1.12 (0.36)

   Urinary organs

420

1.74 (0.90 to 4.94)

16.0 (12.6 to 19.8)

306

1.30 (0.60 to 3.87)

12.8 (9.2 to 16.9)

0.88 (0.22)

   Female genital

345

1.37 (0.67 to 5.37)

17.2 (13.4 to 21.5)

214

1.23 (0.50 to 5.23)

14.1 (9.8 to 19.3)

0.98 (0.63)

Pancreas and other GI organs

176

1.27 (0.61 to 3.57)

13.2 (8.6 to 18.7)

99

1.33 (0.43 to 4.90)

15.1 (8.9 to 22.9)

-b

Stomach

503

1.57 (0.74 to 5.44)

17.7 (14.4 to 21.3)

305

1.60 (0.60 to 5.60)

17.0 (12.9 to 21.6)

0.98 (0.38)

   Thyroid

77

1.81 (0.87 to 10.34)

24.9 (15.7 to 35.2)

56

1.27 (0.50 to 5.17)

18.6 (9.5 to 30.0)

-b

   Breast

375

1.40 (0.57 to 4.97)

17.1 (13.3 to 21.3)

223

1.40 (0.60 to 6.47)

18.9 (13.8 to 24.6)

1.17 (0.48)

Skin

100

2.30 (0.97 to 9.10)

21.3 (13.7 to 30.0)

83

1.83 (0.60 to 6.33)

18.1 (10.6 to 27.3)

-b

   Brain and nervous system

280

2.40 (1.17 to 7.60)

18.0 (13.5 to 23.0)

228

1.97 (0.83 to 7.13)

15.8 (11.2 to 21.2)

1.18 (0.50)

   Colorectal

1,019

1.91 (0.80 to 9.60)

22.8 (20.2 to 25.5)

650

1.77 (0.60 to 7.07)

18.8 (15.8 to 22.0)

1.47 (0.23)

   Male genital

435

1.81 (0.77 to 7.14)

18.6 (14.9 to 22.5)

303

2.17 (0.70 to 9.20)

19.9 (15.4 to 24.8)

1.15 (0.41)

Others

197

1.47 (0.77 to 7.30)

20.8 (15.3 to 26.7)

145

1.03 (0.40 to 3.70)

14.9 (9.5 to 21.3)

-b

Acute comorbidities

       

   Acute renal failure

630

0.90 (0.50 to 1.80)

7.4 (5.4 to 9.8)

359

0.90 (0.37 to 1.93)

8.4 (5.6 to 11.9)

0.44 (0.20)

   Septicemia

2,013

1.02 (0.56 to 2.40)

9.8 (8.5 to 11.2)

1,155

0.93 (0.37 to 2.60)

10.2 (8.5 to 12.2)

0.94 (0.24)

   Shock

1,038

0.89 (0.44 to 2.07)

9.0 (7.3 to 10.8)

547

0.87 (0.33 to 2.40)

9.4 (7.0 to 12.1)

0.96 (0.20)

   GI hemorrhage

941

1.40 (0.60 to 4.70)

15.0 (12.8 to 17.4)

559

1.20 (0.40 to 4.27)

14.2 (11.4 to 17.3)

1.12 (0.26)

   Other injury and poisoning

729

2.90 (1.00 to 16.57)

28.4 (25.1 to 31.8)

392

2.07 (0.77 to 8.50)

21.8 (17.7 to 26.1)

1.61 (0.45)

Cerebrovascular disease

592

2.37 (0.89 to 12.14)

25.2 (21.7 to 28.9)

426

2.67 (0.83 to 12.23)

25.0 (20.8 to 29.4)

1.61 (0.38)

Concurrent organ disorder

(chronic comorbidities)

       

   Hypertension

615

2.60 (0.89 to 16.04)

27.3 (23.7 to 31.0)

354

2.20 (0.80 to 8.90)

21.7 (17.3 to 26.4)

1.83 (0.44)

   COPD

615

2.10 (0.87 to 9.97)

23.0 (19.6 to 26.4)

428

2.00 (0.67 to 8.73)

20.6 (16.8 to 24.6)

1.34 (0.38)

Hospital level

       

   District

977

1.40 (0.63 to 4.04)

12.6 (10.5 to 14.8)

694

1.40 (0.57 to 5.03)

14.3 (11.7 to 17.1)

1.17 (0.31)

   Regional

3,058

1.44 (0.64 to 4.57)

14.4 (13.2 to 15.8)

1,772

1.27 (0.50 to 3.87)

12.2 (10.7 to 13.8)

1.04 (0.22)

   Medical center

4,976

1.67 (0.70 to 8.02)

20.5 (19.3 to 21.6)

2,672

1.40 (0.53 to 5.07)

15.6 (14.2 to 17.1)

1.37 (0.18)

  1. aCI, confidence interval; COPD, chronic obstructive pulmonary disease; GI, gastrointestinal; IQR, interquartile range; MV, mechanical ventilation; SE, standard error of the mean. bLife expectancy could not be calculated because of violation of the assumption of constant excess hazard or small numbers.