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Table 1 Linear mixed models for renal blood flow (RBF) and cerebral blood flow (CBF).

From: Renal macro- and microcirculation autoregulatory capacity during early sepsis and norepinephrine infusion in rats

RBF

Coefficient

95% confidence interval

P

Fixed effects

   

MAP (mmHg)

0.05

0.01; 0.15

<0.001

NE infusion

-0.90

-1.24; -0.57

<0.001

Sepsis

-0.26

-0.72; 0.2

0.3

Interaction MAP×T100 mmHga

-0.01

-0.01; -0.001

0.001

Random effects

   

Interindividual standard deviation

0.78

0.61; 0.98

 

Intraindividual standard deviation

   

   Control

1.45

1.27; 1.7

<0.0001a

   Sepsis

0.9

0.81; 1

 

   NE infusion

0.53

0.46; 0.6

 

   NE+Sepsis

0.39

0.35; 0.44

 

CBF

Coefficient

95% confidence interval

P

Fixed effects

   

MAP (mmHg)

0.02

0.02; 0.03

<0.001

NE infusion

1.83

1.24; 2.40

<0.001

Sepsis

0.76

0.15; 1.37

0.01

Interaction MAP × NEc

-0.02

-0.02; -0.01

<0.001

Interaction MAP×T100 mmHga

0.013

0.01; 0.002

<0.001

Random effects

   

Interindividual standard deviation

0.99

0.77; 1.27

 

Intraindividual standard deviation

   

   Control

1.01

0.88; 1.16

<0.001a

   Sepsis

0.91

0.8; 1.03

 

   NE infusion

0.38

0.33; 0.43

 

   NE+Sepsis

0.62

0.55 ; 0.7

 
  1. aInteraction MAP × threshold 100 mmHg.
  2. bFor between-groups comparison.
  3. cInteraction MAP × NE infusion.
  4. MAP: mean arterial pressure; NE: norepinephrine.