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Table 2 Ventilatory parameters of HFO-TGI sessions, oxygenation index, and respiratory mechanics.

From: High-frequency oscillation and tracheal gas insufflation in patients with severe acute respiratory distress syndrome and traumatic brain injury: an interventional physiological study

Ventilatory technique mPaw (cm H2O) Frequency (Hz) ΔP (cm H2O) TGI flow (L/min) Oxygenation Index Pplateau (cm H2O) Cst (ml/cm H2O)
Pre HFO-TGI CMV 20.5 ± 3.1 NA NA NA 26.0 ± 8.5 30.4 ± 4.5 37.8 ± 9.2
HFO-TGI (4 hours) 31.6 ± 3.9 3.5 ± 0.4 80.9 ± 7.3 3.5 ± 0.4 20.6 ± 10.5* NA NA
HFO-TGI (8 hours) 30.9 ± 4.3 3.6 ± 0.6 80.4 ± 8.5 3.6 ± 0.8 17.5 ± 7.8* NA NA
HFO-TGI (12 hours) 30.2 ± 5.0 3.7 ± 0.9 80.1 ± 8.6 3.7 ± 0.9 15.3 ± 5.9* NA NA
Post HFO-TGI CMV 19.5 ± 3.0 NA NA NA 15.3 ± 5.9* 28.2 ± 4.6* 45.3 ± 13.1*
  1. Values are mean ± SD. CMV, conventional mechanical ventilation; HFO, high-frequency oscillation; TGI tracheal gas insufflation; pre-HFO-TGI CMV, corresponds to either the baseline CMV period of study day 1 or the 60-minute period that followed the 11-hour period of post-HFO-TGI CMV of the preceding study day (see also Figure 1 and corresponding legend); mPaw, mean airway pressure, ΔP, oscillatory pressure amplitude; Pplateau, end-inspiratory plateau airway pressure; Cst, static respiratory system compliance; NA, not applicable.
  2. *P < 0.01 versus pre-HFO-TGI CMV.
  3. § P < 0.01 versus HFO-TGI at 4 hours.