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Table 1 Lung function

From: High positive end-expiratory pressure: only a dam against oedema formation?

 

Baseline

Ventilation with no PEEP (ZEEP phase)

P

  

0 h

6 h

12 h

18 h

 

End-inspiratory airway pressure (cmH2O)

10 ± 1

14 ± 3*

13 ± 2*

13 ± 3*

13 ± 3*

0.002

Transpulmonary pressure (cmH2O)

5 ± 2

10 ± 3*

9 ± 3*

9 ± 3*

10 ± 4*

0.001

Arterial oxygen

tension (mmHg)

222 ± 43

187 ± 58

181 ± 44

180 ± 47

186 ± 24

0.11

Arterial carbon dioxide tension (mmHg)

41 ± 3

36 ± 4

39 ± 4

38 ± 3

39 ± 3

0.16

  1. Respiratory system mechanics, lung mechanics and gas exchange at baseline and during ventilation with no PEEP (ZEEP phase) (18 h). End-inspiratory airway pressure was recorded during a 5-sec end-inspiratory pause. P values refer to one-way RM ANOVA (on ranks if appropriate). *P <0.05 vs. baseline (Holm-Sidak or Dunn's method). PEEP, positive end-expiratory pressure; ZEEP, zero end-expiratory pressure; RM ANOVA, repeated measures analysis of variance.
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Critical Care

ISSN: 1364-8535