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Table 3 Inflammatory markers in the endotoxin-exposed piglets (median and range) (pg/mg protein, except plasma where pg/mg)

From: Mechanical ventilation worsens abdominal edema and inflammation in porcine endotoxemia

 

Liver

Intestine

Lung

Plasma

Median (range)

IL-6

TNFα

IL-6

TNFα

IL-6

TNFα

IL-6

TNFα

CPAP 5

2.06

(1.7-2.4)

1.67*

(1.7-2.5)

1.91*

(1.1-2.3)

1.10

(0.8-1.6)

20.65

(12.9-34.7)

37.1

(31.1-45.9)

1526

(1526-2500)

566.0

(410-1132)

PEEP 5

5.53

(1.8-9.3)

5.18

(2.4-9.3)

6.21

(2.2-7.8)

2.70

(1.0-4.8)

34.2

(9.2-42.4)

43.9

(22.1-46.6)

2500

(1104-2500)

590.3

(288-724)

PEEP 15

2.87

(1.8-9.7)

3.88

(2.2-8.1)

3.23

(1.2-6.4)

2.24

(1.5-2.7)

23.1

(7.7-37.8)

44.1

(31.4-48.0)

953.9

(445-2500)

482.6

(291-818)

  1. aSignificantly different from PEEP.