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Table 2 Hemodynamics and abdominal pressures at baseline and at 150 and 300 minutes (median and range).

From: Mechanical ventilation worsens abdominal edema and inflammation in porcine endotoxemia

CO SB Healthy     
L/min PEEP 5 Healthy 3.8; 2.2-4.8 3.7; 2.4-4.4   3.7; 2.7-5.1
     CPAP 5 LPS 2.7; 1.9-3.0
  PEEP 5 LPS 2.6; 1.8-3.9 2.5; 1.7-5.3 PEEP 5 LPS 2.1; 1.8-2.93
     PEEP 15 LPS 1.9; 1.5-2.74
HR SB Healthy 109.5; 95-123 97.5; 81-105   97.5; 89-103
bpm PEEP 5 Healthy 107.0; 78-125 109.0; 76-132   107; 72-132
     CPAP 5 LPS 107.0; 93-117
  PEEP 5 LPS 88.2; 63-120 120.6; 87-1462 PEEP 5 LPS 105; 86-117
     PEEP 15 LPS 107.5; 95-127
MAP SB Healthy 82.5; 59-92 67.5; 60-71   68.5; 58-70
mm Hg PEEP 5 Healthy 72.5; 59-112 77.0; 56-103   83.0; 56-1111
     CPAP 5 LPS 88.5; 76-90
  PEEP 5 LPS 80.0; 57-115 74.2; 58-104 PEEP 5 LPS 81.0; 65-94
     PEEP 15 LPS 69.0; 59-78
CVP SB Healthy     
mm Hg PEEP 5 Healthy 8.5; 6-9 9; 5-10   8.5; 5-9
     CPAP 5 LPS 6.5; 5-9
  PEEP 5 LPS 7.5; 5-9 7.2; 4-11 PEEP 5 LPS 9.0; 3-11
     PEEP 15 LPS 9.5; 9-134
MPAP SB Healthy     
mm Hg PEEP 5 Healthy 18.0; 17-24 17.5; 15-26   17.0; 16-25
     CPAP 5 LPS 34.5; 29-38
  PEEP 5 LPS 16.3; 14-21 37.1; 25-482 PEEP 5 LPS 35.5; 25-45
     PEEP 15 LPS 33.5; 31-40
APP SB Healthy     
mm Hg PEEP 5 Healthy 60.8; 44.5-100 63; 42-86.5   70.3; 43.5-96
     CPAP 5 LPS 68.5; 62-773
  PEEP 5 LPS 67.9; 37.5-69.5 55.7; 31-62 PEEP 5 LPS 63.8; 43-81
     PEEP 15 LPS 43.5; 31.6-65.0*
IAP SB Healthy     
mm Hg PEEP 5 Healthy 14.0; 5.5-18 13.5; 8-20   13.3; 8.5-21
     CPAP 5 LPS 17.5; 12-23.4
  PEEP 5 LPS 11.7; 5-25 19.0; 11-292 PEEP 5 LPS 16.0; 10-22
     PEEP 15 LPS 22.5; 13-31.5
  1. Note that the pigs given endotoxin (LPS) were all ventilated with PEEP 5 for the first 150 minutes (2.5 hours) and then either maintained on MV + PEEP 5 or switched to MV + PEEP 15 or SB + CPAP 5 for the next 2.5 hours (until 300 minutes); n = 6 in all groups. Significances (P < 0.05) after correction for multiple comparisons (Bonferroni):
  2. Comparison with:
  3. 1: SB Healthy
  4. 2: Baseline
  5. 3: 150 minutes
  6. 4: CPAP 5 LPS
  7. 5: PEEP 5 LPS
  8. *Difference of borderline significance between MV + PEEP 15 and CPAP 5 (0.05 <P < 0.10; correction for multiple comparisons).