Table 3 Medication regimen in 57 subjects at the time of transdiaphragmatic twitch pressure measurementsa
From: Diaphragm weakness in mechanically ventilated critically ill patients
Subject number | Antibiotics | Other medications | Steroid regimen over entire ICU stay |
|---|---|---|---|
1 | Midazolam, metoprolol, hydralazine, calcium acetate, famotidine | ||
2 | Piperacillin/tazobactam, vancomycin, levofloxacin, flagyl | Enoxaparin, omeprazole, dobutamine | Hydrocortisone 100 mg every 8 hours × 4 days |
3 | Metoprolol, haloperidol, insulin, aspirin | ||
4 | Piperacillin/tazobactam, vancomycin, levofloxacin | Midazolam, fentanyl, pantoprazole | |
5 | Famotidine, trazadone | Methylprednisolone 1 g/day × 3 days, prednisone 60 mg/day × 2 days, 40 mg/day × 3 days, 30 mg/day × 2 days, 20 mg/day × 2 days, 10 mg/day × 2 days | |
6 | Piperacillin/tazobactam, vancomycin, fluconazole | Midazolam, fentanyl, insulin, lactulose, levothyroxine, norepinephrine, pantoprazole | Hydrocortisone 50 mg every 6 hours × 1 day |
7 | Piperacillin/tazobactam | Midazolam, alprazolam, fentanyl, insulin, famotidine, heparin | |
8 | Vancomycin | Midazolam, fentanyl, insulin, famotidine, heparin, simvastatin, gabapentin, venlafaxine, calcium gluconate | Hydrocortisone 50 mg every 8 hours × 8 days |
9 | Midazolam, lorazepam, omeprazole, ursodiol, clonidine, levetiracetam, ondansetron, metaclopramide, hydralazine, heparin | ||
10 | Piperacillin/tazobactam, vancomycin | Midazolam, famotidine, aspirin, clopidogrel, insulin, heparin, metaclopramide, docusate | Prednisone 20 mg/day × 3 days, Hydrocortisone 100 mg every 8 hours × 2 days |
11 | Midazolam, protonix, amitryptyline, bupropion, carvedilol, clonazepam, folic acid, acetaminophen, digoxin, ondansetron, heparin, tacrolimus | Methylprednisolone 60 mg every 12 hours × 3 days | |
12 | Vancomycin, clindamycin, tamiflu | Midazolam, fentanyl, morphine, heparin, insulin, pantoprazole, bumetanide | Methylprednisolone 60 mg/day × 4 days, prednisone 40 mg/day × 3 days |
13 | Midazolam, enoxaparin, famotidine, insulin, metoprolol, aspirin, hydralazine, lisinopril, simvastatin | ||
14 | Vancomycin, levofloxacin, flagyl, aztreonam | Midazolam, fentanyl, heparin | Methylprednisolone 60 mg every 12 hours × 6 days |
15 | Vancomycin | Propofol, omeprazole, heparin, amlodipine | |
16 | Midazolam, fentanyl, protonix, ondansetron, darbepoetin, folic acid, cyanocobalamin, hydralazine, amldipine, lisinopril | ||
17 | Vancomycin, levofloxacin | Midazolam, fentanyl, protonix, insulin, lactulose, levothyroxine, sertraline, hydralazine, gabapentin, carvedilol | |
19 | Vancomycin, piperacillin/tazobactam, levofloxacin | Heparin, hydralazine, labetalol, metoprolol, levetiracetam, lorazepam, omeprazole, phenytoin | Prednisone 20 mg/day × 2 days |
20 | Vancomycin | Midazolam, morphine, amlodipine, labetalol, metoprolol, protonix, phenytoin, heparin | |
21 | Vancomycin, tobramycin, ampicillin/sulbactam | Midazolam, fentanyl, heparin, ibuprofen, amiodarone, metoprolol, omeprazole | |
22 | Vancomycin, levofloxacin | Famotidine, heparin, metaclopramide, diphenhydramine | |
23 | Vancomycin, doripenem, colistin | Bumetanide, midazolam, ascorbic acid, famotidine, insulin, vitamin A, zinc, aripiprazole, escitalopram, heparin | |
24 | Paroxetine, pramipexole, simvastatin, omeprazole, heparin, midazolam, insulin, metoprolol, bumetanide | ||
25 | Midazolam, heparin, omeprazole, haloperidol, olanzapine, insulin | Prednisone 40 mg/day × 6 days | |
26 | Famotidine, darbepoetin, amlodipine, labetolol, folic acid, thiamine, dexmedetomidine, heparin | ||
27 | Doripenem, doxycycline, micafungin, flagyl | Midazolam, fentanyl, promethazine, pantoprazole, levetiracetam, propofol, lactulose | Prednisone 50 mg every 8 hours × 8 days |
28 | Midazolam, haloperidol, omeprazole, levothyroxine, heparin, insulin, furosemide | ||
29 | Doripenem, tobramycin, fluconazole, erythromycin | Morphine, ondansetron, rifaximin, pantoprazole, lactulose, insulin, aspirin, heparin, levetriacetam, midazolam, phenytoin, vasopressin | |
30 | Aspirin, benztropine, famotidine, gabapentin, hydrochlorothiazide, metoclopramide, miralax, insulin, heparin, valproic acid, docusate | Methylprednisolone 125 mg every 6 hours × 2 days | |
31 | Azathioprine, bumetanide, clopidogrel, ezetimibe, famotidine, fentanyl, furosemide, heparin, metoprolol, midazolam, nitroglycerin patch, omeprazole, provastatin | Methylprednisilone 125 mg every 6 hours × 3 days, 40 mg every 6 hours × 2 days, prednisone 60 mg/day × 5 days | |
32 | Vancomycin, gentamycin, aztreonam | Midazolam, fentanyl, aspirin, carbemazepam, haloperidol, metoprolol, omeprazole, phenytoin, insulin, heparin | Methylprednisolone 60 mg every 6 hours × 6 days |
33 | Linezolid | Midazolam, lorazepam, fentanyl, aspirin, digoxin, insulin, metoprolol, famotidine, heparin | |
34 | Vancomycin, piperacillin/tazobactam, micofungin | Midazolam, fentanyl, insulin, aspirin, amlodipine, metaclopramide, famotidine, heparin | Methylprednisolone 100 mg every 12 hours × 9 days |
35 | Vancomycin, piperacillin/tazobactam, micofungin, colistin, bactrim | Foscarnate, pantoprazole, diphenhydramine, insulin, fludrocortisone, levothyroxine, ursodiol | Methylprednisolone 10 mg × 1 day |
36 | Vancomycin, meraopenum, valgancyclovir, cefipime, dapsone, levofloxacin | Ondansetron, omeprazole, metoprolol, mycophenolate mofetil, sildenafil | Prednisone 25 mg/day × 250 days |
37 | Piperacillin/tazobactam, vancomycin, levofloxacin | Midazolam, fentanyl, aspirin, heparin, omeprazole, simvastatin | Methylprednisolone 40 mg/day × 2 days, prednisone 40 mg/day × 1 day, prednisone 20 mg/day × 3 days |
38 | Flagyl, levofloxacin, aztreonam | Midazolam, fentanyl, morphine, norepinephrine, vasopressin, famotidine, heparin | |
39 | Doripenam, colistimethate, vancomycin | Midazolam, fentanyl, lortab, zolpidem, metoprolol, omeprazole, heparin | |
40 | Vancomycin, piperacillin/tazobactam, levofloxacin | Midazolam, fentanyl, metaclopramide, aspirin, azathioprine, clopidogrel, furosemide, ondansetron, simvastatin, famotidine, heparin | Prednisone 20 mg/day × 7 days |
41 | Vancomycin, piperacillin/tazobactam, clindamycin | Midazolam, fentanyl, propofol, insulin, omeprazole | |
42 | Vancomycin, cefipime, levofloxacin, acyclovir | Midazolam, fentanyl, ondansetron, pantoprazole, heparin | |
44 | Midazolam, fentanyl, haloperidol, insulin, famotidine, heparin | Methylprednisolone 125 mg every 6 hours × 2 days | |
45 | Midazolam, fentanyl, ondansetron, insulin, omeprazole, heparin | Hydrocortisone 100 mg every 8 hours × 3 days | |
46 | Linezolid, piperacillin/tazobactam, tobramycin | Midazolam, Diltiazem, mycophenolate mofetil, tacrolimus, famotidine, insulin, heparin | Hydrocortisone 100 mg every 8 hours × 6 days, prednisone 40 mg/day × 3 days |
47 | Vancomycin, cefipime, levofloxacin | Midazolam, aspirin, captopril, furosemide, simvastatin, insulin | Prednisone 40 mg/day × 3 days, 30 mg/day × 2 days |
49 | Midazolam, aspirin, atorvastatin, bisoprolol, clopidogrel, fluticasone, folic acid, pantoprazole, heparin | Methylprednisolone 60 mg every 6 hours × 4 days, 40 mg every 12 hours × 2 days, prednisone 40 mg/day × 1 day | |
50 | Vancomycin, aztreonam, tobramycin, daptomycin | Midazolam, hydroxyzine, darbepoetin, levothyroxine, ferrous sulfate, ergocalciferol, pancrelipase, omeprazole | Hydrocortisone 20 mg every 12 hours × 37 days |
51 | Vancomycin, piperacillin/tazobactam, doripenam, fluconazaole | Midazolam, fentanyl, furosemide, pancrelipase, magnesium oxide, famotidine, insulin, heparin | |
52 | Vancomycin, piperacillin/tazobactam, daptomycin | Midazolam, fentanyl, levothyroxine, darbepoetin, fluticasone, lactulose, paroxetime, insulin, heparin | Hydrocortisone 100 mg every 8 hours × 5 days |
53 | Tamiflu, piperacillin/tazobactam, cefipime, daptomycin, doripenam | Midazolam, darbepoetin, bumetanide, famotidine, insulin, heparin | |
54 | Vancomycin, piperacillin/tazobactam | Morphine, oxycodone, furosemide, famotidine, insulin, heparin | Hydrocortisone 50 mg every 6 hours × 3 days |
55 | Vancomycin, piperacillin/tazobactam, levofloxacin, daptomycin | Ferrous sulfate, folic acid, levothyroxine, metaclopramide, pravastatin, digoxin tacrolimus, omeprazole, heparin | |
56 | Daptomycin, linezolid, tobramycin, colistin, zithromax | Midazolam, fentanyl, dexmedetomidine, omeprazole, heparin | |
57 | Vancomycin, piperacillin/tazobactam, levofloxacin, tamiflu | Midazolam, fentanyl, clonazepam, gabapentin, famotidine, insulin, heparin | |
58 | Piperacillin/tazobactam | Midazolam, morphine, furosemide, metoprolol, citalopram, pantoprazole, aspirin, acetazolamide, insulin, heparin | Methylprednisolone 60 mg every 8 hours × 4 days, prednisone 60 mg/day × 5 days, 40 mg/day × 5 days, 30 mg/day × 5 days |
59 | Vancomycin, cefipime, levofloxacin | Midazolam, fentanyl, dopamine, norepinephrine, simvastatin, aspirin, omeprazole, heparin | Hydrocortisone 100 mg every 8 hours × 3 days, 50 mg every 8 hours × 2 day, 50 mg every 12 hours × 7 days |
60 | Vancomycin, cefipime, tobramycin | Midazolam, fentanyl, norepinephrine, pantoprazole, heparin |