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Table 6 Comparison of patients with ischemia versus no ischemia on ECG.

From: Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine

Variable Ischemia
(N =56)
No ischemiaa (N = 60) P value
Age, years 64.1 (48.0, 77.1) 63.0 (53.5, 73.3) 0.808
Male, n (%) 40 (71) 41 (68) 0.840
Surgical patient, n (%) 21 (38) 25 (42) 0.706
APACHE II 29.9 (7.5) 27.4 (8.0) 0.150
Preexisting conditions, n (%)    
    Ischemic heart disease 10 (18) 4 (7) 0.088
    Diabetes 13 (23) 10 (17) 0.486
Baseline lactate 2.0 (1.6, 4.5) 2.6 (1.5, 3.9) 0.441
More-severe shock,b n (%) 28 (50) 33 (55) 0.710
Vasopressin, n (%) 31 (55) 32 (53) 0.854
Days alive free of mechanical ventilation (first 28 days) 0.0 (0.0, 13.0) 2.0 (0.0, 17.0) 0.165
ICU stay,c days 13.0 (6.0, 31.0) 11.5 (6.0, 20.0) 0.518
Hospital stay,c days 27.0 (11.0, 77.0) 35.5 (16.0, 77.5) 0.703
28-day mortality,d n (%)
95% CI
26 (47)
34%-60%
22 (37)
24%-49%
0.263
90-day mortality,d n (%)
95% CI
33 (60)
47% to 73%
27 (45)
32% to 58%
0.136
  1. Baseline and outcome data for patients with ischemia and those with no ischemia on ECG.
  2. Continuous variables are presented as median and first and third quartiles. Categoric variables are presented as number and percentage. P value is based on Fisher Exact test or Wilcoxon rank-sum test. Five patients had no data for ECG diagnosis of ischemia. aDefined as no ischemia on any ECG for both readers. bDefined as treatment with 15 μg/min of norepinephrine or the equivalent at randomization. cICU and hospital stay from time of admission to ICU. dMortality outcome of one patient was unknown and excluded from the calculation.