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Table 6 Comparison of patients with ischemia versus no ischemia on ECG.

From: Cardiac ischemia in patients with septic shock randomized to vasopressin or norepinephrine

Variable

Ischemia

(N =56)

No ischemiaa (N = 60)

P value

Age, years

64.1 (48.0, 77.1)

63.0 (53.5, 73.3)

0.808

Male, n (%)

40 (71)

41 (68)

0.840

Surgical patient, n (%)

21 (38)

25 (42)

0.706

APACHE II

29.9 (7.5)

27.4 (8.0)

0.150

Preexisting conditions, n (%)

   

    Ischemic heart disease

10 (18)

4 (7)

0.088

    Diabetes

13 (23)

10 (17)

0.486

Baseline lactate

2.0 (1.6, 4.5)

2.6 (1.5, 3.9)

0.441

More-severe shock,b n (%)

28 (50)

33 (55)

0.710

Vasopressin, n (%)

31 (55)

32 (53)

0.854

Days alive free of mechanical ventilation (first 28 days)

0.0 (0.0, 13.0)

2.0 (0.0, 17.0)

0.165

ICU stay,c days

13.0 (6.0, 31.0)

11.5 (6.0, 20.0)

0.518

Hospital stay,c days

27.0 (11.0, 77.0)

35.5 (16.0, 77.5)

0.703

28-day mortality,d n (%)

95% CI

26 (47)

34%-60%

22 (37)

24%-49%

0.263

90-day mortality,d n (%)

95% CI

33 (60)

47% to 73%

27 (45)

32% to 58%

0.136

  1. Baseline and outcome data for patients with ischemia and those with no ischemia on ECG.
  2. Continuous variables are presented as median and first and third quartiles. Categoric variables are presented as number and percentage. P value is based on Fisher Exact test or Wilcoxon rank-sum test. Five patients had no data for ECG diagnosis of ischemia. aDefined as no ischemia on any ECG for both readers. bDefined as treatment with 15 μg/min of norepinephrine or the equivalent at randomization. cICU and hospital stay from time of admission to ICU. dMortality outcome of one patient was unknown and excluded from the calculation.