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Figure 6 | Critical Care

Figure 6

From: Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery

Figure 6

Effect of imatinib or nilotinib treatment on mRNA expression of platelet-derived growth factor receptor in mice with lipoplysaccharide-induced acute lung injury. The mRNA expression of platelet-derived growth factor receptor-ß (PDGFR) was measured in lung tissues. In real-time PCR analysis, to normalize the content of cDNA samples, the comparative threshold (CT) cycle method, consisting of the normalization of the number of target gene copies versus the housekeeping gene β-actin, was used. LPS, lipopolysaccharide; C, cyclophosphamide; I, imatinib; N, nilotinib. Asterisks indicate significant differences from the C + LPS group (**P <0.01).

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