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Figure 2 | Critical Care

Figure 2

From: Effect of tyrosine kinase inhibitors, imatinib and nilotinib, in murine lipopolysaccharide-induced acute lung injury during neutropenia recovery

Figure 2

Effect of imatinib or nilotinib on the histopathological changes in the lung in mice lipopolysaccharide-induced acute lung inury. Representative images of H&E-stained lung sections from four experimental groups: (A) control group; the lung structure is normal, (B) cyclophosphamide (C) + lipopolysaccharide (LPS) group; LPS induced acute lung damage with interstitial edema, hemorrhage, thickening of the alveolar wall and infiltration of inflammatory cells into the interstitium and alveolar spaces, (C) C + LPS + imatinib (I) group, (D) C + LPS + nilotinib (N) group; lung injury was attenuated by treatment with imatinib or nilotinib.

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Critical Care

ISSN: 1364-8535