A multicenter, prospective validation study of the Japanese Association for Acute Medicine disseminated intravascular coagulation scoring system in patients with severe sepsis

Table 4 Disease severity, organ dysfunction and mortality for JAAM DIC score on inclusion day (day 1)

	JAAM DIC score
	0 ( n = 19)	1 ( n = 89)	2 ( n = 143)	3 ( n = 81)	4 ( n = 59)	5 ( n = 105)	6 ( n = 59)	7 ( n = 19)	8 ( n = 50)
APACHE II score	22.3 ± 7.8	20.2 ± 7.6	21.8 ± 7.5	23.7 ± 8.6	23.4 ± 7.9	26.1 ± 9.1^bc	25.1 ± 7.0^b	25.0 ± 9.1	26.0 ± 9.2^b
SIRS score	1.7 ± 0.5	2.8 ± 1.0	3.2 ± 0.7	3.4 ± 0.7	2.9 ± 1.0^ad	3.3 ± 0.7^ab	3.5 ± 0.5^ab	2.7 ± 1.0^a	3.6 ± 0.5^abc
SOFA score	6.5 ± 3.7	5.7 ± 3.3	6.7 ± 2.9	8.0 ± 3.5	9.4 ± 3.4^bc	10.0 ± 4.2^abcd	11.4 ± 3.2^abcd	11.5 ± 3.4^abcd	11.9 ± 3.6^abcd
SOFA peak score during study period	6.8 ± 3.8	6.1 ± 3.4	7.4 ± 3.3	8.7 ± 3.6	10.0 ± 3.5^bc	11.0 ± 4.2^abcd	11.9 ± 3.3^abcd	12.3 ± 3.1^abcd	13.0 ± 3.8^abcd
MODS (%)	42.1	32.6	37.1	54.3	55.9^bc	61.9^bc	72.9^abcd	63.2^b	76.0^abcd
28-day mortality (%)	5.3	10.1	18.9	19.8	27.1^b	37.1^abcd	27.1^ab	31.6^ab	28.0^ab
Hospital mortality (%)	10.5	14.6	25.2	25.9	30.5^ab	43.8^abcd	35.6^ab	42.1^ab	38.0^ab

APACHE, Acute Physiology and Chronic Health Evaluation; DIC, disseminated intravascular coagulation; JAAM, Japanese Association for Acute Medicine; MODS, multiple organ dysfunction syndrome; SIRS, Systemic Inflammatory Response Syndrome; SOFA, Sequential Organ Failure Assessment. Analyses of variance of APACHE II, SIRS and SOFA are as follows: P <0.001, ^aP <0.05 versus 0, ^bP <0.05 versus 1, ^cP <0.05 versus 2, ^dP <0.05 versus 3.

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