Continuous renal replacement therapy outcomes in acute kidney injury and end-stage renal disease: a cohort study

Table 1 Baseline demographics and comorbidities

	AKI (n= 725)	ESRD (n= 138)	P-value
Age, years	63 (53, 74)	66 (54, 76)	0.14
Male	454 (63%)	93 (67%)	0.29
White race	564 (78%)	110 (80%)	0.62
Medical ICU	378 (52%)	93 (67%)	0.001
Lactate, mmol/L	4.3 (1.9, 8.9)	3.2 (1.5, 5.0)	0.05
Albumin, g/dL	2.8 (2.3, 3.2)	3.1 (2.6, 3.4)	0.002
BUN, mg/dL(at admission)	34 (20, 54)	N/A	N/A
Creatinine, mg/dL(at admission)	1.8 (1.2, 2.9)	N/A	N/A
BUN, mg/dL(at CRRT initiation)	54 (34, 84)	N/A	N/A
Creatinine, mg/dL(at CRRT initiation)	3.4 (2.4, 4.7)	N/A	N/A
Charlson score	2 (1, 4)	5 (4, 6)	<0.001
Length of stay, days	21 (10, 38)	19 (9, 32)	0.10
Duration of CRRT, days	5 (3, 10)	4 (3, 8)	0.10
Diabetes mellitus	208 (29%)	75 (54%)	<0.001
Chronic pulmonary disease	148 (20%)	23 (17%)	0.31
Liver disease	131 (18%)	19 (14%)	0.22
Malignancy	99 (14%)	14 (10%)	0.26
Myocardial infarction	125 (18%)	40 (29%)	0.002
Congestive heart failure	209 (29%)	57 (42%)	0.004
Peripheral vascular disease	111 (15%)	38 (28%)	<0.001
Cerebrovascular accident	91 (13%)	29 (21%)	0.008

Laboratory values used are the closest values to the initiation of CRRT, unless labeled otherwise. Values are median (interquartile range) or number (%). Medical ICU is defined as admission to a medical ICU (medical, cardiology, neurology) versus non-medical ICU (general surgery, transplant surgery, cardiothoracic surgery, burn, trauma). AKI, acute kidney injury; ESRD, end-stage renal disease; BUN, blood urea nitrogen; CRRT, continuous renal replacement therapy; NA, not assessed.

ISSN: 1364-8535