Time course of the percentages of CD19+ lymphocytes that express CD23+ (A), CD69+ (B), CD5+ (C), CD95+ (D) and CD80+ (E) antigens in patients with septic shock during their stay in the ICU. Data presented are for survivors (black triangles) and nonsurvivors (white triangles). The dotted line represents the mean value recorded in the healthy controls (n = 36). At ICU admission, study patients were 34 survivors and 18 nonsurvivors; at day 3, 34 survivors and 13 nonsurvivors; at day 7, 34 survivors and 11 nonsurvivors; at day 14 and at day 28, 34 survival patients were studied. All values are expressed as means ± SEM. *P < 0.05 for survivors or nonsurvivors vs healthy controls; †P < 0.05 for survivors vs nonsurvivors.