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Table 3 Survival in old and young mechanically ventilated rats

From: Susceptibility to ventilator induced lung injury is increased in senescent rats

Survival >3 hours of MV Complete ventilation period (4 h)
_Age young old young old
_VT 8 ml/kg 100% 100% 87% 93%
_VT 16 ml/kg 100% 87% 100% 80%
_VT 24 ml/kg 93% 73% 80% 33% *
  1. N = 15 per group;
  2. Animals were ventilated with either low (8 ml/kg), high (16 ml/kg) or very high (24 ml/kg) tidal volume (VT). * P = 0.013 vs. old animals with same tidal volume at the same time point.