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Table 1 White blood cell counts and pulmonary variables in non-ventilated old and non-ventilated young rats (n = 4/group).

From: Susceptibility to ventilator induced lung injury is increased in senescent rats

 

Old rats

Young rats

P

TWBC (/μl)

4,800 ± 524

9,037 ± 638

0.02

_PMN in blood (/μl)

867 ± 146

1,162 ± 65

Ns

_Macrophages in BAL (/μl)

11,744 ± 2,172

10,882 ± 2,646

Ns

_Protein in BAL (mg/l)

69 ± 35

97 ± 30

Ns

_Lung wet/dry weight ratio

4.68 ± 0.09

4.65 ± 0.06

Ns

_PaO2 at FiO2 1.0 (mmHg)

270 ± 60

446 ± 10

0.029

_PMN in BAL (/μl)

Not detectable in 3; low counts in 1 animal

Not detectable

n.a.

  1. Values are mean ± SEM.
  2. BAL, bronchoalveolar lavage; FiO2, fraction of inspired oxygen; n.a., not applicable; PaO2, arterial oxygen tension; PMN, polymorphonuclear neutrophils; TWBC, total white blood cell count