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Table 4 Results of separate multiple linear regression models with ventilator-free days, ICU-free days, and specific organ failure-free days as the outcome variables and GDF-15 quartile as the predictor variable.

From: Growth differentiation factor-15 and prognosis in acute respiratory distress syndrome: a retrospective cohort study

 

Quartile 2

Quartile 3

Quartile 4

 

β*

95% CI

P value

β *

95% CI

P value

β *

95% CI

P value

Ventilator-free days

-2.91

-5.61,

-0.21

0.03

-5.27

-8.01,

-2.53

<0.01

-6.56

-9.38, -3.74

<0.01

ICU-free days

-1.88

-4.39, 0.62

0.14

-5.25

-7.81,

-2.71

<0.01

-6.25

-8.87, -3.63

<0.01

Organ failure-free days

         

Cardiovascular

-0.85

-3.32, 1.61

0.50

-2.38

-4.87, 0.12

0.06

-6.03

-8.61, -3.45

<0.01

CNS

-2.03

-4.78, 0.72

0.15

-5.66

-8.44,

-2.88

<0.01

-8.69

-11.56,

-5.81

<0.01

Coagulation

-0.19

-2.60, 2.22

0.88

-3.03

-5.46,

-0.59

0.02

-7.49

-10.01,

-4.97

<0.01

Renal

-0.45

-2.87, 1.98

0.72

-4.73

-7.18,

-2.27

<0.01

-10.0

-12.56,

-7.49

<0.01

Hepatic

-0.01

-2.42, 2.41

0.99

-2.52

-4.96, -0.07

0.04

-8.49

-11.02,

-5.97

< 0.01

  1. Patients in GDF-15 quartile 1 served as the control group and, therefore, are not included in the table. *Parameter estimates shown are the difference when compared to patients in GDF-15 quartile 1 after adjusting for APACHE III score. CNS, central nervous system; 95% CI, 95% confidence interval.