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Table 2 Comparison of factors associated with 15-day mortality.

From: Plasma levels of mitochondrial and nuclear DNA in patients with massive pulmonary embolism in the emergency department: a prospective cohort study

 

Healthy controls

(n = 37)

Submassive PE

(n = 37)

Massive

PE

(n = 37)

Mann-Whitney U-test

(Massive vs Submassive PE)

Massive PE

Survivors

(n = 19)

Massive PE

Non-survivors

(n = 18)

Mann-Whitney U-test

(Non-survivors vs Survivors)

 

Troponin I (ng/ml)

0.003

(0.001-0.005)

0.009

(0.006-0.012)

0.019

(0.012-0.028)

-3.040

p <0.002

0.016

(0.012-0.023)

0.023

(0.014-0.28)

-2.042

p <0.04

 

D- dimer (μg/ml)

0.5

(0.1-0.8)

7.8

(4.1-10.4)

12.6

(8.2-15.8)

-2.309

p <0.021

11.9

(8.2-15.3)

13.7

(10.6-15.8)

-1.004

NS

 

NT-proBNP (pg/ml)

235

(130-350)

570

355-840

1720

(770-3185)

-2.750

p <0.006

1510

(770-2140)

1940

(950-3185)

-1.332

NS

 

H-FBAP (ng/ml)

1.4

(0.8-2.1)

3.1

(1.6-4.2)

6.8

(5.7-7.8)

-3.520

p <0.001

6.4

(5.7-7.4)

7.3

(6.1-7.8)

-2.839

p <0.05

 

Plasma n- DNA (GE/ml)

520

(230-760)

1245

(680-2315)

3325

(1080-5790)

-3.039

p <0.002

2285

(1280-4010)

4450

(1130-5780)

-2.750

p <0.016

 

Plasma mt- DNA (GE/ml)

185

(70-430)

870

(365-1690)

2970

(1050-5485)

-4.151

p <0.000

1830

(1050-3215)

4220

(2110-5510)

-3.769

p <0.001

 

Plasma sFas (pg/ml)

1070

(530-1650)

3355

(640-6720)

8940

(5330-13270)

-2.408

p <0.013

7680

(6330-9400)

10570

(9050-12870)

-2.355

p <0.019

 

Plasma sFasL (pg/ml)

460

(355-540)

510

(285-580)

790

(570-920)

-1.265

NS

755

(570-845)

810

(640-920)

-1.265

NS

 
  1. Data are median (IQR);
  2. COPD: chronic obstructive pulmonary disease; DVP: deep venous thrombosis; pro-BNP: pro-Brain Natriuretic Peptide; H-FBAP: heart-type fatty acid-binding protein; sFas: soluble Fas molecule; sFasL: soluble Fas ligand molecule.