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Table 3 Immunohistochemical analyses and Western blots

From: Antithrombin attenuates myocardial dysfunction and reverses systemic fluid accumulation following burn and smoke inhalation injury: a randomized, controlled, experimental study

Variable

sham

control

rhAT

Myeloperoxidase activity (U/mL)

105 (104; 106)

132 (120; 139)#

114 (105; 118)†

p38-MAPK (arbitrary units)

2.3 (1.8; 3.5)

6.1 (5.4; 6.5)#

2.8 (2.3; 3.0)†

TNF-α (arbitrary units)

2.1 (1.8; 2.1)

2.7 (2.6; 2.8)#

2.0 (1.6; 2.4)†

IL-6 (arbitrary units)

1.4 (1.3; 2.0)

4.0 (3.0; 4.6)#

2.1 (1.9; 2.8)†

  1. #, P <0.05 vs. sham; † , P <0.05 vs. control; data are represented as median with interquartile range (25th; 75th); each group n = 6
  2. IL-6, interleukin 6; p38-MAPK, p38-mitogen-activated protein kinases; rhAT, recombinant human antithrombin III; TNF-α, tumor necrosis factor alpha.