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Table 2 Histology injury score and lung wet-to-dry ratio at the end of the experiment

From: Inhaled aerosolized insulin ameliorates hyperglycemia-induced inflammatory responses in the lungs in an experimental model of acute lung injury

  NL NG HG HG-VI HG-AI
Alveolar congestion 0.11 ± 0.33 #
0.67 ± 0.48
## **
2.48 ± 0.51
## ** §§
1.71 ± 0.56
## §§ ¶¶
0.90 ± 0.30
Edema 0 ± 0 0.19 ± 0.4 ## **
2.24 ± 0.70
## ** §§
1.67 ± 0.80
§§ ¶¶
0 ± 0
Infiltration/
aggregation of neutrophils
0 ± 0 ##
0.95 ± 0.59
## **
2.33 ± 0.73
## §§
1.33 ± 0.66
## §§
1.05 ± 0.59
Wet-to-dry
ratio
NA 7.99 ± 1.16 8.37 ± 1.52 8.69 ± 2.07 * §
6.33 ± 1.00
  1. NL, normal healthy control group; NG, acute lung injury with normoglycemia group; HG, acute lung injury with hyperglycemia group; HG-VI, acute lung injury with hyperglycemia treated with intravenous insulin group; HG-AI, acute lung injury with hyperglycemia treated with aerosolized insulin group; NA, not available. Values shown are mean ± SD. ##P <0.01, #P <0.05 compared with the NL group; **P <0.01, *P <0.05 compared with the NG group; §§P <0.01, §P <0.05 compared with the HG group; ¶¶P <0.01 compared with the HG-VI group.