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Table 2 Histology injury score and lung wet-to-dry ratio at the end of the experiment

From: Inhaled aerosolized insulin ameliorates hyperglycemia-induced inflammatory responses in the lungs in an experimental model of acute lung injury

 

NL

NG

HG

HG-VI

HG-AI

Alveolar congestion

0.11 ± 0.33

#

0.67 ± 0.48

## **

2.48 ± 0.51

## ** §§

1.71 ± 0.56

## §§ ¶¶

0.90 ± 0.30

Edema

0 ± 0

0.19 ± 0.4

## **

2.24 ± 0.70

## ** §§

1.67 ± 0.80

§§ ¶¶

0 ± 0

Infiltration/

aggregation of neutrophils

0 ± 0

##

0.95 ± 0.59

## **

2.33 ± 0.73

## §§

1.33 ± 0.66

## §§

1.05 ± 0.59

Wet-to-dry

ratio

NA

7.99 ± 1.16

8.37 ± 1.52

8.69 ± 2.07

* §

6.33 ± 1.00

  1. NL, normal healthy control group; NG, acute lung injury with normoglycemia group; HG, acute lung injury with hyperglycemia group; HG-VI, acute lung injury with hyperglycemia treated with intravenous insulin group; HG-AI, acute lung injury with hyperglycemia treated with aerosolized insulin group; NA, not available. Values shown are mean ± SD. ##P <0.01, #P <0.05 compared with the NL group; **P <0.01, *P <0.05 compared with the NG group; §§P <0.01, §P <0.05 compared with the HG group; ¶¶P <0.01 compared with the HG-VI group.