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Table 1 Arterial blood gas and hemodynamic data

From: Inhaled aerosolized insulin ameliorates hyperglycemia-induced inflammatory responses in the lungs in an experimental model of acute lung injury

   Baseline After Injury One hour after treatment End of experiment
pH NG 7.38 ± 0.04 7.35 ± 0.06 7.27 ± 0.04 7.29 ± 0.03
  HG 7.39 ± 0.04 7.34 ± 0.05 7.28 ± 0.05 7.26 ± 0.05
  HG-VI 7.39 ± 0.04 7.37 ± 0.06 7.30 ± 0.03 7.32 ± 0.02
  HG-AI 7.39 ± 0.02 7.33 ± 0.06 7.34 ± 0.05 7.34 ± 0.05
PaCO2 (mmHg) NG 40 ± 6 46 ± 12 57 ± 7 58 ± 3
  HG 39 ± 4 49 ± 11 60 ± 5 64 ± 11
  HG-VI 39 ± 4 45 ± 11 47 ± 5 47 ± 6
  HG-AI 38 ± 3 48 ± 5 50 ± 8 53 ± 7
PO2/FiO2 NG 620 ± 36 105 ± 25 503 ± 71** 565 ± 62**
  HG 617 ± 16 74 ± 18 420 ± 124** 378 ± 118**
  HG-VI 616 ± 28 77 ± 19 586 ± 68** 609 ± 55** #
  HG-AI 637 ± 21 80 ± 21 588 ± 53** 637 ± 13** ##
HR (beats/minute) NG 236 ± 34 260 ± 44 254 ± 36 261 ± 42
  HG 259 ± 39 271 ± 34 269 ± 38 253 ± 43
  HG-VI 232 ± 49 249 ± 33 259 ± 24 255 ± 22
  HG-AI 239 ± 21 256 ± 15 270 ± 20 258 ± 32
MAP (mmHg) NG 90 ± 17 106 ± 28 99 ± 23 88 ± 25
  HG 85 ± 13 106 ± 24 95 ± 20 109 ± 25
  HG-VI 85 ± 7 93 ± 15 71 ± 13 71 ± 18
  HG-AI 90 ± 8 102 ± 7 90 ± 10 103 ± 13
  1. NG, acute lung injury with normoglycemia group; HG, acute lung injury with hyperglycemia group; HG-VI, acute lung injury with hyperglycemia treated with intravenous insulin group; HG-AI, acute lung injury with hyperglycemia treated with aerosolized insulin group; HR, heart rate; MAP, mean arterial pressure. All values are mean ± SD. **P <0.01 compared with after injury; ##P <0.01, #P <0.05 compared with the HG group.