Table 4 Data regarding animals subjected to prolonged pneumonia-induced ALI

Number of animals

11

11

11

11

Animal weight (g)

383 ± 13

378 ± 19

413 ± 35

401 ± 47

Animal survival (number, %)

8 (73)

9 (82)

9 (82)

8 (73)

Duration of animal survival (hours)

65.5 ± 11.2

64.8 ± 16.2

63.3 ± 19.4

63.3 ± 16.1

Instilled E. coli bacterial load (CFU × 10⁴)

5.0 ± 1.0

5.0 ± 1.0

5.0 ± 1.0

5.0 ± 1.0

Peak airway pressure (mm Hg)

8.1 ± 1.4

6.5 ± 1.0

7.4 ± 1.0

8.0 ± 1.3

Lung homogenate bacterial counts (CFU × 10⁴)

1.1 (0.7, 3.1)

51.3 (3.1, 96)*

20.7 (15.9, 36.2)*

19.3 (16.5, 34.6)*

BAL neutrophils (× 10⁹/ml)

3.7 ± 3.3

2.3 ± 0.8

3.8 ± 2.2

1.7 ± 0.9

BAL mononuclear cells (× 10⁹/ml)

2.3 ± 1.8

0.4 ± 0.2*

0.9 ± 0.6*

0.4 ± 0.2*