Table 1 Data regarding animals subjected to acute pneumonia-induced ALI

Number of animals

12

12

12

12

Animal weight (g)

456 ± 55

486 ± 54

469 ± 52

438 ± 86

Bacteria instilled (CFU × 10¹⁰)

1.1 ± 0.2

2.1 ± 0.2

2.6 ± 2.0

2.1 ± 2.2

Baseline arterial PO₂ (kPa)

18.7 ± 0.5

18.7 ± 0.8

18.8 ± 0.8

18.7 ± 0.8

Baseline static compliance (ml/mm Hg)

0.93 ± 0.1

0.95 ± 0.1

0.99 ± 0.2

0.87 ± 0.2

Animal survival (number, %)

4 (33)

7 (58)

11 (92)*

5 (42)

Duration of animal survival (hours)

2.75(2, 4)

4 (1.5, 4)

4 (4, 4)*

3 (1.75, 4)

Lung homogenate bacterial counts (CFU × 10⁹)

0.8 (0.4, 1.7)

1.4 (0.2, 2.6)

0.6 (0.4, 0.9)

0.7 (0.4, 0.9)

BAL neutrophils (× 10⁷/ml)

5.9 (1.5, 8.4)

3.7 (1.5, 8.9)

6.2 (1.8, 6.7)

8.5 (1.1, 9.1)

BAL mononuclear cells (× 10⁷/ml)

2.2 (1.4, 9.1)

0.57 (2.7, 7.0)

1.5 (1.2, 9.3)

1.8 (1.1, 9.6)