Figure 2
From: Bench-to-bedside review: Future novel diagnostics for sepsis - a systems biology approach
DNA microarrays in genomics. The core principle behind DNA microarray technology is hybridization of genomic DNA fragments to a fixed probe. The collected genomic DNA is amplified and labeled and is then hybridized to a cDNA chip that is loaded with various SNPs. The sample DNA will hybridize with greater frequency only to specific SNPs associated with that person. Those spots on the microarray chip will fluoresce with greater intensity. The workflow of this entire process is 3 to 5 days depending on the technology used.