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Table 3 Comparison between night and day periods of time to achieve each component of the 6-h bundle (hours)

From: Differences in compliance with Surviving Sepsis Campaign recommendations according to hospital entrance time: day versus night

6-h bundle component

Day, h

Night, h

P value

Serum lactate measurement, median (IQR)

6:97 (1:27-25:18)

4:48 (0:83-14:02)

0.018*

Blood cultures drawn, median (IQR)

8:17 (2:74-25:54)

4:06 (1:55-10:83)

<0.001*

Antibiotic administration, median (IQR)

8:18 (4:25-16:17)

4:95 (2:02-9:89)

<0.001*

CVP >8 mmHg, median (IQR)

10:94 (5:17-22:50)

7:83 (1:88-17:37)

0.010*

SvcO2 >70%, median (IQR)

10:65 (8:78-22:17)

2:47 (1:02-29:64)

0.222*

  1. aMann-Whitney test.
  2. CVP: Central venous pressure; IQR: Interquartile range; SvcO2: Central venous oxygen saturation.