Components of the 6-h bundle | Total, n(%) | Day, n(%) (08:30 to 20:30) | Night, n(%) (20:30 to 08:30) | P value |
---|---|---|---|---|
1 - Serum lactate measurement | 156 (52) | 82 (49) | 74 (57) | 0.171a |
2 - Blood cultures drawn | 140 (47) | 63 (37) | 77 (59) | <0.001a |
3 - Antibiotic administration within the first 3 h of hospital entrance time | 70 (25) | 28 (18) | 42 (33) | 0.003a |
4 - Fluids administration in patients with hypotension | 200 (100) | 107 (100) | 93 (100) | - |
5 - Administration of vasopressors when indicated | 197 (100) | 107 (99) | 90 (100) | - |
6 - CVP >8 mmHg | 75 (36) | 33 (29) | 42 (45) | 0.021a |
7 - SvcO2 >70% | 9 (4) | 2 (2) | 7 (7) | 0.082b |
Compliance with 6-h bundle, n (%) | 5 (2) | 1 (1) | 4 (3) | 0.172a |