Table 2 Organ failures, ICU management, and outcome.

Scoring systems (IQR)

   Child-Pugh score

9 (7-11)

10 (8.25-11)

0.22

   MELD day 1

25 (17-33.8)

26 (20.2-32.8)

0.43

   SAPS II day 1

56 (38-70.5)

59 (42-76)

0.10

   SOFA day 1

14 (8.5-17.5)

13 (9-15)

0.18

Biological findings at ICU admission (IQR)

   Serum creatinine level, μmol/L

140 (96-199)

147 (105-235)

0.93

   Serum bilirubin level, μmol/L

48 (35-110)

68 (44.2-140.5)

0.23

   Arterial blood lactate level, mmol/L

4.2 (2-6.5)

4.3 (2.2-7.9)

0.68

   Serum sodium, mmol/L

134 (130.5-139)

135.5 (129.2-139)

0.74

   Serum protein level, g/L

54 (44.5-61)

59 (50-66.8)

0.05

   Factor V, %

42 (33-64)

46 (33-60)

0.70

   INR

2 (1.5-2.8)

2 (1.6-3.1)

0.69

   White blood cells, 10³/mm³

13.6 (6.2-19)

10.7 (6.4-15.2)

0.45

   C-reactive protein, mg/L

101 (60-167)

75 (34-127)

0.24

Mechanical ventilation

45 (95.7)

39 (93)

0.34

   Tidal volume, mL/kg (IQR)^a

8.6 (7.3-9.9)

7 (6.1-7.9)

<0.001

   Lowest Pao₂/Fio₂ ratio (IQR)

101 (80-150)

117 (86-206)

0.17

   ARDS

16 (34)

14 (33.3)

1

Renal replacement therapy

34 (72.3)

22 (52.4)

0.08

Antimicrobial treatment

   β-lactam

45 (95.7)

41 (97.6)

1

   Quinolone

19 (40.4)

12 (25.5)

0.27

   Aminoglycoside

23 (49)

22 (52.4)

0.83

   Glycopeptide

9 (19.1)

6 (14.3)

0.58

Combination therapy

31 (64)

34 (81)

0.15

Inadequacy of initial antimicrobial treatment

5 (10.6)

3 (7.1)

1

Fluid loading within the first 3 days

   Crystalloids, L (IQR)

6 (3-8.9)

3 (1.7-4.5)

<0.001

   Albumin resuscitation

4 (8.5)

24 (57.1)

<0.001

Adjuvant therapies of sepsis

   Intensive insulin therapy

15 (31.9)

35 (83.3)

<0.001

   Low-dose glucocorticoids

21 (44.7)

34 (81)

<0.001

   Activated protein C

0

2 (4.8)

1

ICU survival

8 (17)

17 (40)

0.02

Hospital survival

3 (6)

12 (29)

0.009

6-month survival

3 (6)

9 (21)

0.06