From: Increased survival of cirrhotic patients with septic shock
Characteristic | 1997-2004 47 patients | 2005-2010 42 patients | P |
---|---|---|---|
Age (years, IQR) | 55 (46.5-62) | 58 (53-65) | 0.08 |
Male gender | 36 (76.5) | 26 (62) | 0.49 |
Knaus scale | 0.15 | ||
Mild limitation (B) | 6 (12.8) | 10 (23.8) | |
Important limitation (C) | 25 (53.2) | 17 (40.5) | |
Severe limitation (D) | 16 (34) | 15 (35.7) | |
Charlson score (IQR)a | 1 (0-1) | 1 (0-2) | 0.51 |
Co-morbidities | |||
Chronic heart failure | 4 (8.5) | 3 (7) | 0.81 |
COPD | 2 (4.3) | 3 (7) | 0.79 |
Diabetes | 6 (12.8) | 10 (24) | 0.27 |
Cancer | 8 (17) | 8 (19) | 0.80 |
Hepatocellular carcinoma | 3 | 3 | |
Otherb | 5 | 5 | |
Immunosuppressionc | 6 (12.8) | 2 (4.8) | 0.27 |
Cause of cirrhosisd | |||
Alcohol +/- virus | 38 (80.1) | 34 (80.1) | 1 |
Chronic Hepatitis B virus infection | 2 (4.3 ) | 0 | 0.50 |
Chronic Hepatitis C virus infection | 6 (12.8) | 4 (9.5) | 0.74 |
Primary biliary cirrhosis | 2 (4.3) | 2 (4.8) | 1 |
Undetermined | 3 (6.4) | 2 (4.8) | 1 |
Persistent alcohol abuse | 26 (55.3) | 22 (52.3) | 0.83 |
Nosocomial septic shock | 13 (27.7) | 14 (33.3) | 0.67 |
Primary source of infection | |||
Respiratory | 18 (38.3) | 19 (45.2) | 0.53 |
Abdominal | 10 (21.3) | 16 (38,1) | 0.10 |
Spontaneous peritonitis | 8 (17) | 14 (33.3) | |
Secondary peritonitis | 2 (4.3) | 2 (4.8) | |
Urinary tract | 6 (12.8) | 4 (9.5) | 0.49 |
Others | |||
CNS | 3 (6.4) | 0 | 0.10 |
Arthritis | 1 (2.1) | 1(2.4) | 1 |
Isolated bacteriemia | 2 (4.2) | 0 | 0.50 |
Unknown | 7 (14.9) | 2 (4.8) | 0.16 |
Bacteremia | 20 (42.6) | 14 (33.3) | 0.39 |
Type of organisms | |||
Gram-positive cocci | 15 (31.9) | 13 (30.9) | 1 |
Gram-negative bacilli | 17 (36.2) | 11 (23.8) | 0.25 |
Fungi | 2 (4.3) | 2 (4.8) | 1 |
Culture negative | 12 (25.5) | 8 (19) | 0.61 |
Polymicrobial sepsis | 1 (2.1) | 8 (19) | 0.01 |
Multi-drug resistant bacteria | 2 (4.3) | 8 (17) | 0.04 |