Figure 3From: Balanced versus chloride-rich solutions for fluid resuscitation in brain-injured patients: a randomised double-blind pilot studyTime course of acid-base status in the saline group and the balanced group. Hyperchloraemic acidosis was defined as the association of hyperchloraemia (>108 mmol/L) with strong ion difference (SID) <40 mmol/L. SID = (Na + K + Ca + Mg) - (Cl + lactate). {AU: OK to delete Kaplan? OK Or are words missing?} According to Stewart et al. (A) pH is independently influenced by three biological values: first, the SID (B) and chloraemia (C); second, the total weak acid concentration composed of phosphor (D) and albumin (E); and third, the partial pressure of carbon dioxide in arterial blood (PaCO2) (F). Results are given as medians (IQR). *P < 0.05 versus saline group (significant group effect). Na: sodium, K: potassium, Ca: calcium, Mg: magnesium, Cl: chloride.Back to article page