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Table 3 Sepsis interventions related to septic shock among the five groups of BMI

From: Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study

Variable < 18.50
Number = 196
18.50 to 24.99
Umber = 1,020
25.0 to 29.99
Number = 816
30.0 to 39.99
Number = 680
≥ 40
Number = 170
P value
Vasopressors used, Number (%)
   Dopamine 117 (59.7) 594 (58.2) 465 (57.0) 408 (60.0) 91 (53.5) 0.54
   Norepinephrine 122 (62.2) 566 (55.5) 480 (58.8) 362 (53.2) 86 (50.6) 0.04
   Phenylephrine 58 (29.6) 336 (32.9) 255 (31.3) 219 (32.2) 48 (28.2) 0.70
   Epinephrine 12 (6.1) 45 (4.4) 41 (5.0) 31 (4.6) 15 (8.8) 0.15
   Dobutamine 16 (8.2) 98 (9.6) 84 (10.3) 75 (11.0) 18 (10.6) 0.77
Vasopressor dose - at six hours, mean (SD)
   Dopamine (μcg/kg/minute) 7.7 (7.3) 6.7 (4.9) 6.5 (4.7) 6.4 (4.3) 6.2 (5.1) 0.22
   Norepinephrine (μcg/kg/minute) 0.39 (0.41) 0.37 (0.60) 0.33 (0.43) 0.30 (0.47) 0.18 (0.18) 0.05
   Phenylephrine (μcg/kg/minute) 3.4 (4.1) 2.2 (2.1) 2.1 (2.3) 2.0 (2.4) 1.2 (1.4) 0.003
   Epinephrine (μcg/kg/minute) 0.85 (0.61) 0.30 (0.26) 0.33 (0.73) 0.18 (0.12) 0.21 (0.18) 0.04
   Dobutamine (μcg/kg/minute) 5.1 (1.7) 4.4 (2.5) 4.7 (2.9) 4.0 (2.8) 4.4 (2.5) 0.82
Sepsis specific therapy
   Activated protein C, number (%) 9 (4.6) 36 (3.5) 29 (3.6) 42 (6.2) 13 (7.7) 0.01
   Low-dose steroids, number (%) 73 (37.2) 305 (29.9) 256 (31.4) 222 (32.7) 46 (27.1) 0.19
   Inappropriate antimicrobials therapy, number (%) 46 (23.5) 188 (18.4) 160 (19.6) 120 (17.7) 31 (18.2) 0.43
   Single versus combined antimicrobial therapy, number (%) 142 (72.5) 711 (69.7) 568 (69.6) 456 (67.1) 118 (69.4) 0.62
   Delay in antimicrobial therapy, mean (SD) 17.8 (30.3) 13.9 (24.0) 15.1 (26.0) 12.6 (18.8) 16.7 (29.9) 0.12
Others
   Pulmonary artery catheter, number (%) 91 (46.4) 513 (50.3) 428 (52.5) 386 (56.8) 89 (52.4) 0.04
   Pulmonary capillary wedge pressure, (mmHG), mean (SD) 15.0 (5.2) 16.5 (6.1) 17.6 (6.1) 18.6 (6.4) 20.5 (6.7) < 0.001
   Cardiac output (L/minute), mean (SD) 6.4 (2.8) 7.1 (3.2) 7.6 (3.2) 7.7 (3.4) 8.7 (3.5) < 0.001
   Cardiac index(L/minute/m2), mean (SD) 4.1 (1.7) 4.1 (1.7) 4.0 (1.6) 3.8 (1.5) 3.9 (1.5) 0.11
  1. BMI, body mass index.