Number (%) | < 18.50 Number = 196 | 18.50 to 24.99 Number = 1,020 | 25.0 to29.99 Number = 816 | 30.0 to 39.99 Number = 680 | ≥ 40 Number = 170 | P value |
---|---|---|---|---|---|---|
Total culture negative | 49 (25.0) | 270 (26.5) | 242 (29.7) | 204 (30.0) | 53 (31.2) | 0.28 |
Total culture positive | 147 (75.0) | 750 (73.5) | 574 (70.3) | 476 (70.0) | 117 (68.8) | Â |
Gram-negative organisms | 72 (36.7) | 384 (37.7) | 281 (34.4) | 230 (33.8) | 45 (26.5) | 0.05 |
   Escherichia coli | 23 (11.7) | 163 (16.0) | 115 (14.1) | 97 (14.3) | 19 (1.2) | 0.32 |
   Klebsiella | 16 (8.2) | 62 (6.1) | 41 (5.0) | 36 (5.3) | 7 (4.1) | 0.38 |
   Pseudomonas aeruginosa | 13 (6.6) | 68 (6.7) | 48 (5.9) | 28 (4.1) | 8 (4.7) | 0.23 |
   Enterobacter species | 5 (2.6) | 27 (2.7) | 21 (2.6) | 25 (3.7) | 1 (0.6) | 0.25 |
   Haemophilus influenzae | 6 (3.1) | 12 (1.2) | 10 (1.2) | 8 (1.2) | 3 (1.8) | 0.29 |
   Acinetobacter species | 4 (2.0) | 10 (1.0) | 6 (0.8) | 11 (1.6) | 2 (1.2) | 0.38 |
   Other Gram-negative bacilli | 5 (2.6) | 42 (4.1) | 40 (4.9) | 25 (3.7) | 5 (2.9) | 0.49 |
Gram-positive organisms | 41 (20.9) | 247 (24.2) | 183 (22.4) | 168 (24.7) | 60 (35.3) | 0.007 |
   Staphylococcus aureus | 19 (9.7) | 110 (10.8) | 81 (9.9) | 71 (10.4) | 22 (12.9) | 0.81 |
   Streptococcus pneumonia | 9 (4.6) | 60 (5.9) | 37 (4.5) | 37 (5.4) | 8 (4.7) | 0.74 |
   Streptococci faecalis | 4 (2.0) | 19 (1.9) | 17 (2.1) | 17 (2.5) | 6 (3.5) | 0.68 |
   Streptococcus faecium | 2 (1.0) | 11 (1.1) | 8 (1.0) | 4 (0.6) | 3 (1.8) | 0.69 |
   Group A streptococcus species | 2 (1.0) | 18 (1.8) | 17 (2.1) | 14 (2.1) | 10 (5.9) | 0.01 |
   Other β-hemolytic streptococci | 3 (1.5) | 12 (1.2) | 10 (1.2) | 13 (1.9) | 8 (4.7) | 0.01 |
   Other Gram-positive bacilli | 2 (1.0) | 17 (1.7) | 13 (1.6) | 12 (1.8) | 3 (1.8) | 0.97 |
Fungi/Yeast | 20 (10.2) | 77 (7.6) | 84 (10.3) | 62 (9.1) | 8 (4.7) | 0.08 |
   Candida albicans | 11 (5.6) | 44 (4.3) | 50 (6.1) | 37 (5.4) | 7 (4.1) | 0.46 |
   Other candida/yeast | 9 (4.6) | 33 (3.2) | 34 (4.2) | 25 (3.7) | 1 (0.6) | 0.18 |
Anaerobes | 10 (5.1) | 26 (2.6) | 17 (2.1) | 14 (2.1) | 4 (2.4) | 0.15 |
Other organisms | 4 (2.0) | 16 (1.6) | 9 (1.1) | 2 (0.3) | 0 | 0.04 |
Site of infection | Â | Â | Â | Â | Â | Â |
Lung | 95 (48.5) | 445 (43.6) | 301 (36.9) | 226 (33.2) | 53 (31.2) | < 0.001 |
   Pneumonia | 91 (46.4) | 435 (42.7) | 296 (36.3) | 223 (32.8) | 51 (30.0) | 0.45 |
   Empyema | 4 (2.0) | 10 (1.0) | 5 (0.6) | 3 (0.4) | 2 (1.2) | 0.22 |
Intraabdominal | 53 (27.0) | 299 (29.3) | 268 (32.8) | 228 (33.5) | 53 (31.2) | 0.20 |
   Intraabdominal abscess | 5 (2.6) | 23 (2.3) | 23 (2.8) | 28 (4.1) | 8 (4.7) | 0.15 |
   Ascending Cholangitis | 2 (1.0) | 23 (2.3) | 14 (1.7) | 13 (1.9) | 0 | 0.28 |
   Cholecystitis | 1 (0.5) | 9 (0.9) | 14 (1.7) | 12 (1.8) | 1 (0.6) | 0.26 |
   Ischemic bowel/bowel infarction | 7 (3.6) | 48 (4.7) | 51 (6.3) | 35 (5.2) | 5 (2.9) | 0.27 |
   Viscous bowel perforation | 21 (10.7) | 104 (10.2) | 104 (12.8) | 66 (9.7) | 20 (11.8) | 0.34 |
   Spontaneous bacterial peritonitis | 3 (1.5) | 31 (3.0) | 14 (1.7) | 17 (2.5) | 1 (0.6) | 0.16 |
   Clostridium difficile enterocolitis/toxic megacolon | 7 (3.6) | 25 (2.5) | 18 (2.2) | 12 (1.8) | 2 (1.2) | 0.49 |
   Infected pancreatic necrosis | 0 | 4 (0.4) | 11 (1.4) | 16 (2.4) | 3 (1.8) | 0.002 |
   Others | 7 (3.6) | 32 (3.1) | 19 (2.3) | 29 (4.3) | 13 (7.7) | 0.009 |
Skin and soft tissue | 14 (7.1) | 69 (6.8) | 72 (8.8) | 79 (11.6) | 37 (21.8) | < 0.001 |
   Cellulitis | 2 (1.0) | 7 (0.7) | 11 (1.4) | 19 (2.8) | 12 (7.1) | < 0.001 |
   Necrotizing soft tissue infections | 5 (2.6) | 20 (2.0) | 16 (2.0) | 23 (3.4) | 12 (7.1) | 0.001 |
   Others | 7 (3.6) | 42 (4.1) | 45 (5.5) | 37 (5.4) | 13 (7.7) | 0.22 |
Genitourinary | 17 (8.7) | 92 (9.0) | 80 (9.8) | 70 (10.3) | 18 (10.6) | 0.88 |
Intravascular catheter infection | 8 (4.1) | 38 (3.7) | 29 (3.6) | 36 (5.3) | 6 (3.5) | 0.46 |
Primary bloodstream infection (bacteremia without identifiable source) | 8 (4.1) | 49 (4.8) | 44 (5.4) | 37 (5.4) | 7 (4.1) | 0.87 |
Systemically disseminated infection (including yeast and tuberculosis) | 6 (3.1) | 29 (2.8) | 26 (3.2) | 18 (2.7) | 5 (2.9) | 0.98 |
Septic arthritis | 0 | 5 (0.5) | 7 (0.9) | 7 (1.0) | 6 (3.5) | 0.002 |