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Table 2 Microbiologic and sites of infection among different groups of BMI

From: Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study

Number (%) < 18.50
Number = 196
18.50 to 24.99
Number = 1,020
25.0 to29.99
Number = 816
30.0 to 39.99
Number = 680
≥ 40
Number = 170
P value
Total culture negative 49 (25.0) 270 (26.5) 242 (29.7) 204 (30.0) 53 (31.2) 0.28
Total culture positive 147 (75.0) 750 (73.5) 574 (70.3) 476 (70.0) 117 (68.8)  
Gram-negative organisms 72 (36.7) 384 (37.7) 281 (34.4) 230 (33.8) 45 (26.5) 0.05
   Escherichia coli 23 (11.7) 163 (16.0) 115 (14.1) 97 (14.3) 19 (1.2) 0.32
   Klebsiella 16 (8.2) 62 (6.1) 41 (5.0) 36 (5.3) 7 (4.1) 0.38
   Pseudomonas aeruginosa 13 (6.6) 68 (6.7) 48 (5.9) 28 (4.1) 8 (4.7) 0.23
   Enterobacter species 5 (2.6) 27 (2.7) 21 (2.6) 25 (3.7) 1 (0.6) 0.25
   Haemophilus influenzae 6 (3.1) 12 (1.2) 10 (1.2) 8 (1.2) 3 (1.8) 0.29
   Acinetobacter species 4 (2.0) 10 (1.0) 6 (0.8) 11 (1.6) 2 (1.2) 0.38
   Other Gram-negative bacilli 5 (2.6) 42 (4.1) 40 (4.9) 25 (3.7) 5 (2.9) 0.49
Gram-positive organisms 41 (20.9) 247 (24.2) 183 (22.4) 168 (24.7) 60 (35.3) 0.007
   Staphylococcus aureus 19 (9.7) 110 (10.8) 81 (9.9) 71 (10.4) 22 (12.9) 0.81
   Streptococcus pneumonia 9 (4.6) 60 (5.9) 37 (4.5) 37 (5.4) 8 (4.7) 0.74
   Streptococci faecalis 4 (2.0) 19 (1.9) 17 (2.1) 17 (2.5) 6 (3.5) 0.68
   Streptococcus faecium 2 (1.0) 11 (1.1) 8 (1.0) 4 (0.6) 3 (1.8) 0.69
   Group A streptococcus species 2 (1.0) 18 (1.8) 17 (2.1) 14 (2.1) 10 (5.9) 0.01
   Other β-hemolytic streptococci 3 (1.5) 12 (1.2) 10 (1.2) 13 (1.9) 8 (4.7) 0.01
   Other Gram-positive bacilli 2 (1.0) 17 (1.7) 13 (1.6) 12 (1.8) 3 (1.8) 0.97
Fungi/Yeast 20 (10.2) 77 (7.6) 84 (10.3) 62 (9.1) 8 (4.7) 0.08
   Candida albicans 11 (5.6) 44 (4.3) 50 (6.1) 37 (5.4) 7 (4.1) 0.46
   Other candida/yeast 9 (4.6) 33 (3.2) 34 (4.2) 25 (3.7) 1 (0.6) 0.18
Anaerobes 10 (5.1) 26 (2.6) 17 (2.1) 14 (2.1) 4 (2.4) 0.15
Other organisms 4 (2.0) 16 (1.6) 9 (1.1) 2 (0.3) 0 0.04
Site of infection       
Lung 95 (48.5) 445 (43.6) 301 (36.9) 226 (33.2) 53 (31.2) < 0.001
   Pneumonia 91 (46.4) 435 (42.7) 296 (36.3) 223 (32.8) 51 (30.0) 0.45
   Empyema 4 (2.0) 10 (1.0) 5 (0.6) 3 (0.4) 2 (1.2) 0.22
Intraabdominal 53 (27.0) 299 (29.3) 268 (32.8) 228 (33.5) 53 (31.2) 0.20
   Intraabdominal abscess 5 (2.6) 23 (2.3) 23 (2.8) 28 (4.1) 8 (4.7) 0.15
   Ascending Cholangitis 2 (1.0) 23 (2.3) 14 (1.7) 13 (1.9) 0 0.28
   Cholecystitis 1 (0.5) 9 (0.9) 14 (1.7) 12 (1.8) 1 (0.6) 0.26
   Ischemic bowel/bowel infarction 7 (3.6) 48 (4.7) 51 (6.3) 35 (5.2) 5 (2.9) 0.27
   Viscous bowel perforation 21 (10.7) 104 (10.2) 104 (12.8) 66 (9.7) 20 (11.8) 0.34
   Spontaneous bacterial peritonitis 3 (1.5) 31 (3.0) 14 (1.7) 17 (2.5) 1 (0.6) 0.16
   Clostridium difficile enterocolitis/toxic megacolon 7 (3.6) 25 (2.5) 18 (2.2) 12 (1.8) 2 (1.2) 0.49
   Infected pancreatic necrosis 0 4 (0.4) 11 (1.4) 16 (2.4) 3 (1.8) 0.002
   Others 7 (3.6) 32 (3.1) 19 (2.3) 29 (4.3) 13 (7.7) 0.009
Skin and soft tissue 14 (7.1) 69 (6.8) 72 (8.8) 79 (11.6) 37 (21.8) < 0.001
   Cellulitis 2 (1.0) 7 (0.7) 11 (1.4) 19 (2.8) 12 (7.1) < 0.001
   Necrotizing soft tissue infections 5 (2.6) 20 (2.0) 16 (2.0) 23 (3.4) 12 (7.1) 0.001
   Others 7 (3.6) 42 (4.1) 45 (5.5) 37 (5.4) 13 (7.7) 0.22
Genitourinary 17 (8.7) 92 (9.0) 80 (9.8) 70 (10.3) 18 (10.6) 0.88
Intravascular catheter infection 8 (4.1) 38 (3.7) 29 (3.6) 36 (5.3) 6 (3.5) 0.46
Primary bloodstream infection (bacteremia without identifiable source) 8 (4.1) 49 (4.8) 44 (5.4) 37 (5.4) 7 (4.1) 0.87
Systemically disseminated infection (including yeast and tuberculosis) 6 (3.1) 29 (2.8) 26 (3.2) 18 (2.7) 5 (2.9) 0.98
Septic arthritis 0 5 (0.5) 7 (0.9) 7 (1.0) 6 (3.5) 0.002
  1. BMI, body mass index.