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Table 4 Base excess and platelet count (BEP) performance for different cutoffs on the development, validation and replication datasets.

From: A new scoring system derived from base excess and platelet count at presentation predicts mortality in paediatric meningococcal sepsis

Dataset BEP N Sensitivity Specificity Positive predictive value Negative predictive value
  > 0.1 50 0.65 0.88 0.29 0.97
  > 0.2 21 0.44 0.96 0.45 0.96
Development > 0.3 8 0.26 0.99 0.6 0.94
  > 0.4 4 0.15 1 0.75 0.94
  > 0.5 2 0.05 1 0.55 0.93
  > 0.1 110 0.67 0.87 0.29 0.97
  > 0.2 64 0.57 0.94 0.43 0.96
Validation > 0.3 30 0.35 0.98 0.55 0.95
  > 0.4 21 0.29 0.99 0.68 0.95
  > 0.5 11 0.17 1 0.78 0.94
  > 0.1 25 0.85 0.9 0.4 0.99
  > 0.2 16 0.8 0.97 0.7 0.98
Replication > 0.3 11 0.56 0.98 0.72 0.97
  > 0.4 9 0.48 0.99 0.79 0.96
  > 0.5 6 0.36 1 1 0.95
  1. N denotes the number of individuals with BEP score greater than the selected cutoff (for example on the validation dataset there are 110 subjects with a BEP > 0.1).