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Table 2 Demographic and other features of the study population, according to survival (mean with 95% confidence intervals shown, t-test with unequal variance).

From: A new scoring system derived from base excess and platelet count at presentation predicts mortality in paediatric meningococcal sepsis

 

Whole population

Died

Survived

P value

Sex (male, %)

581/1073 (54%)

52/85 (61%)

529/988 (54%)

0.18 (chi square)

Decimal age (years)

5.12 ± 0.30

5.75 ± 1.3

5.06 ± 0.3

0.36

PRISM

12.7 ± 1.2

61.9 ± 6.7

11.0 ± 1.3

< 0.001

GMSPS

7.9 ± 0.2

11.4 ±

7.6 ± 0.3

< 0.001

Rotterdam

13.5 ± 1.6

59.1 ± 8.3

10.2 ± 1.3

< 0.001

WCC (109/L)

14.5 ± 1.3

6.7 ± 1.5

15.1 ± 1.4

< 0.001

Platelets (1012/L)

197 ± 7

100 ± 19

206 ± 6.7

< 0.001

APTT (s)

53 ± 2

104 ± 15

50 ± 2

< 0.001

INR

1.7 ± 0.05

2.7 ± 0.4

1.6 ± 0

< 0.001

Fibrinogen (g/L)

3.7 ± 0.1

1.6 ± 0.4

3.9 ± 0.1

< 0.001

CRP (mg/dL)

107.3 ± 4.8

68.7 ± 12.1

110.1 ± 5

< 0.001

K (mmol/L)

3.7 ± 0

3.9 ± 0.3

3.6 ± 0

0.56

Base excess (mmol/L)

-6.9 ± 0.3

-12.1 ± 1.2

-6.5 ± 0.3

< 0.001

Lactate (mmol/L)

3.7 ± 0.2

7.2 ± 0.9

3.7 ± 0.2

< 0.001

Ventilation

627/1073 (58%)

80/85 (94%)

547/988 (55%)

< 0.0001 (chi square)

Inotropes

675/1073 (63%)

78/85 (96%)

597/988 (60%)

< 0.0001 (chi square)

  1. PRISM, paediatric risk of mortality; GMSPS, Glasgow meningococcal septicaemia prognosis score; WCC, white cell count; APTT, activated partial thromboplastin time; INR, international normalised ratio; CRP, C-reactive protein.