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Table 1 Assessment of disease severity and laboratory markers of sepsis-associated inflammation and organ injury and dysfunction

From: Hepatic excretory function in sepsis: implications from biophotonic analysis of transcellular xenobiotic transport in a rodent model

  

sham

sepsis

 

Unit

mean ± SEM

mean ± SEM

Activity score

1 (active) to 5 (lethargic)

1.0 ± 0.0

3.9 ± 0.2a

Peritoneal exudate

ml

0

5.3 ± 0.5a

Fibrin generation

0 (none) to 3 (massive)

0

2.6 ± 0.2a

White cell count

× 103/μl

5 ± 0.4

0.9 ± 0.1a

Platelets

× 103/μl

504.4 ± 32.1

294.7 ± 53.1a

IL6

pg/ml

407 ± 88

6,013 ± 2426a

LDH

IU/l

233.3 ± 25.7

695.4 ± 65.8a

Ammonia

μmol/l

200.2 ± 21.4

278.4 ± 35.9

AST

IU/l

76.3 ± 11.7

202.3 ± 43.5a

Albumin

g/dL

2.6 ± 0.1

1.5 ± 0.1a

Hematocrit

%

40.2 ± 0.6

49.4 ± 1.2a

  1. aP < 0.05 compared to sham. AST, aspartate aminotransferase; IL6, interleukin-6; LDH, lactate dehydrogenase; SEM, standard error of the mean. N = 12 per group.