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Table 1 Baseline characteristics of the study population of 1,488 intensive care unit patients with septic shock, and survival probabilities at 3, 7, and 28 days (Kaplan-Meier product limit method - EPISS study - 2009 to 2011).

From: The epidemiology of septic shock in French intensive care units: the prospective multicenter cohort EPISS study

   Survival probabilitiesa  
  All ( n = 1,488) 3 days 7 days 28 days P value (log-rank test)
Age (years)      
   <60 428 (28.8%) 86.0% 79.9% 67.8% <0.0001
   60 to <70 277 (25.3%) 82.2% 74.8% 57.8%  
   70 to <80 437 (29.4%) 80.3% 75.0% 54.1%  
   ≥80 246 (16.5%) 78.0% 71.1% 45.7%  
Gender      
   Female 537 (36.1%) 82.7% 76.7% 61.6% 0.04
   Male 951 (63.9%) 81.7% 75.2% 55.4%  
BMI (kg/m²)      
   <20 129 (8.7%) 81.4% 74.4% 55.5% 0.06
   20-25 371 (24.9%) 83.0% 77.0% 56.4%  
   25-30 388 (26.1%) 82.0% 77.8% 59.0%  
   >30 336 (22.6%) 85.7% 79.1% 61.4%  
   N/A 264 (17.7%)     
Co-morbiditiesb      
   Immunosuppressionc 459 (30.9%) 76.7% 66.6% 44.9% <0.0001
Cancer (solid tumors) 226 (49.2%) 77.9% 68.4% 44.5% 0.97
Hematological cancer 142 (30.9%) 69.0% 57.0% 37.0% <0.01
Corticoids 109 (23.8%) 79.8% 71.6% 52.9% 0.55
Transplantation 40 (8.7) 82.5% 77.5% 55.0% 0.15
AIDS 10 (2.2%) 80.0% 70.0% 30.0% 0.63
Other 77 (16.8%) 74.0% 64.0% 48.0% 0.90
   Diabetes mellitus 387 (26.0%) 84.7% 77.7% 55.8% 0.63
   Cirrhosis 133 (8.9%) 79.7% 66.8% 41.7% <0.0001
   Chronic heart failure (NYHA Class III/IV) 160 (10.8%) 78.1% 72.5% 46.1% <0.01
   Chronic respiratory failurec 113 (7.6%) 86.7% 81.4% 57.9% 0.80
   Chronic renal failured 171 (11.6%) 81.5% 75.7% 49.4% 0.04
Number of co-morbidities      
   None 510 (34.3%) 85.5% 81.4% 70.0% <0.0001
   1 633 (42.5%) 80.1% 73.1% 54.7%  
   2 or more 339 (23.1%) 80.6% 72.1% 44.7%  
Knausc      
   A/B 853 (57.4%) 85.5% 80.3% 65.0% <0.0001
   C/D 634 (42.6%) 77.4% 69.5% 47.6%  
SOFA      
   ≥11 823 (55.3%) 72.5% 65.6% 45.0% <0.0001
   <11 665 (44.7%) 93.8% 88.3% 73.3%  
SAPS II      
   ≥56 753 (50.6%) 69.3% 61.3% 40.9% <0.0001
   <56 735 (49.4%) 95.1% 90.4% 74.8%  
Site of infectionb      
   Respiratory tract 798 (53.6%) 84.1% 77.4% 56.7% 0.84
   Abdominal 285 (19.2%) 83.1% 75.0% 58.2% 0.83
   Renal/urinary tract 209 (14.1%) 86.6% 82.8% 69.5% <0.001
   Bloodstream 196 (13.2%) 70.4% 63.3% 49.8% <0.001
   Other 88 (5.9%) 81.8% 75.0% 57.3% 0.99
Type of infection      
   Community-acquired 974 (65.5%) 82.6% 78.1% 61.9% <0.0001
   Nosocomial 514 (34.5%) 80.9% 71.2% 49.6%  
Germ identification      
   Yes 1,000 (67.2%) 81.8% 75.9% 58.8% 0.21
   No 488 (32.8%) 82.6% 75.4% 55.2%  
Type of admission      
   Planned surgery 37 (2.5%) 89.2% 83.8% 64.2% <0.01
   Medical 1,248 (83.9%) 80.7% 74.2% 55.9%  
   Emergency surgery 203 (13.6%) 89.2% 83.2% 67.3%  
Origin of patient 595 (40.0%)     
   Home 23 (1.6%) 84.0% 79.1% 65.3% <0.0001
   Nursing home 870 (58.5%) 95.6% 91.3% 73.9%  
   Transfer   80.3% 73.0% 51.9%  
  1. AIDS, acquired immune deficiency syndrome; BMI, body mass index; N/A, not available; NYHA, New York Heart Association.
  2. aAccording to the Kaplan Meier product-limit method.
  3. bPatients could have more than one comorbidity and/or site of infection.
  4. cOne missing datum.
  5. Two missing data.