Table 4 Weaning variables of patients under invasive mechanical ventilation
Characteristic | All patients (n= 622) | Survivors (n= 354) | Non-survivors (n= 268) | OR (CI 95%) | P- value |
|---|---|---|---|---|---|
General variables - n (%) | Â | Â | Â | Â | Â |
Successful spontaneous breathing trial | 378 (61) | 304 (86) | 74 (28) | 0.06 (0.04 to 0.09) | < 0.001 |
Extubation | 338 (54) | 270 (76) | 68 (25) | 0.11 (0.08 to 0.16) | < 0.001 |
Use of NIV after extubation | 108 (17) | 77 (22) | 31 (12) | 0.52 (0.34 to 0.83) | 0.006 |
Reintubation | 94 (15) | 57 (16) | 37 (14) | 0.94 (0.59 to 1.47) | 0.792 |
Time to reintubation | 1 (0 to 3) | 1 (0 to 3) | 1 (0 to 3) | 1.00 (0.94 to 1.07) | 0.837 |
Time < 48 hours to reintubation | 57 (9) | 30 (8) | 27 (10) | 0.74 (0.38 to 1.47) | 0.400 |
Tracheostomy | 182 (29) | 93 (26) | 89 (33) | 1.37 (0.97 to 1.39) | 0.073 |
Days to tracheostomy | 7 (5 to 11) | 7 (5 to 10) | 9 (6 to 12) | 1.04 (0.99 to 1.10) | 0.057 |
Cause of extubation failure (more than one may apply) - n (%) | Â | Â | Â | Â | Â |
Coma | 41 (6) | 14 (4) | 27 (10) | 3.06 (1.57 to 5.97) | < 0.001 |
Agitation/delirium | 11 (2) | 8 (2) | 3 (1) | 0.54 (0.14 to 2.06) | 0.371 |
Shock | 20 (3) | 3 (1) | 17 (6) | 8.86 (2.56 to 30.6) | < 0.001 |
Ventilator-associated pneumonia | 13 (2) | 6 (2) | 7 (3) | 1.73 (0.57 to 5.21) | 0.330 |
Dyspnea | 50 (8) | 31 (9) | 19 (7) | 0.88 (0.49 to 1.61) | 0.697 |
Cardiac dysfunction | 7 (1) | 2 (0.8) | 5 (2) | 3.71 (0.71 to 19.3) | 0.118 |
Hypoxemia/Hypercapnia | 36 (6) | 16 (5) | 20 (7) | 1.91 (0.97 to 3.76) | 0.063 |
Excessive respiratory secretions | 24 (4) | 14 (4) | 10 (4) | 1.05 (0.45 to 2.40) | 0.912 |