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Table 4 Weaning variables of patients under invasive mechanical ventilation

From: Clinical outcomes of patients requiring ventilatory support in Brazilian intensive care units: a multicenter, prospective, cohort study

Characteristic All patients
(n= 622)
Survivors
(n= 354)
Non-survivors
(n= 268)
OR (CI 95%) P- value
General variables - n (%)      
Successful spontaneous breathing trial 378 (61) 304 (86) 74 (28) 0.06 (0.04 to 0.09) < 0.001
Extubation 338 (54) 270 (76) 68 (25) 0.11 (0.08 to 0.16) < 0.001
Use of NIV after extubation 108 (17) 77 (22) 31 (12) 0.52 (0.34 to 0.83) 0.006
Reintubation 94 (15) 57 (16) 37 (14) 0.94 (0.59 to 1.47) 0.792
Time to reintubation 1 (0 to 3) 1 (0 to 3) 1 (0 to 3) 1.00 (0.94 to 1.07) 0.837
Time < 48 hours to reintubation 57 (9) 30 (8) 27 (10) 0.74 (0.38 to 1.47) 0.400
Tracheostomy 182 (29) 93 (26) 89 (33) 1.37 (0.97 to 1.39) 0.073
Days to tracheostomy 7 (5 to 11) 7 (5 to 10) 9 (6 to 12) 1.04 (0.99 to 1.10) 0.057
Cause of extubation failure (more than one may apply) - n (%)      
Coma 41 (6) 14 (4) 27 (10) 3.06 (1.57 to 5.97) < 0.001
Agitation/delirium 11 (2) 8 (2) 3 (1) 0.54 (0.14 to 2.06) 0.371
Shock 20 (3) 3 (1) 17 (6) 8.86 (2.56 to 30.6) < 0.001
Ventilator-associated pneumonia 13 (2) 6 (2) 7 (3) 1.73 (0.57 to 5.21) 0.330
Dyspnea 50 (8) 31 (9) 19 (7) 0.88 (0.49 to 1.61) 0.697
Cardiac dysfunction 7 (1) 2 (0.8) 5 (2) 3.71 (0.71 to 19.3) 0.118
Hypoxemia/Hypercapnia 36 (6) 16 (5) 20 (7) 1.91 (0.97 to 3.76) 0.063
Excessive respiratory secretions 24 (4) 14 (4) 10 (4) 1.05 (0.45 to 2.40) 0.912