Table 2 Factors associated with hospital mortality in a multivariate analysis

Age

1.03

1.01 to 1.03

< 0.001

SOFA Score excluding respiratory component

1.12

1.05 to 1.19

< 0.001

Charlson comorbidity index

0.002

   0

ref

ref

   1 to 2

1.37

0.92 to 2.04

0.124

   > 2

2.30

1.28 to 3.17

< 0.001

ARDS

0.037

   Absence ARDS

ref

ref

   ARDS mild

1.09

0.68 to 1.73

0.721

   ARDS moderate

1.92

1.11 to 3.35

0.02

   ARDS severe

2.12

1.02 to 4.41

0.045

Mechanical ventilation

0.004

   Successful NIV

ref

ref

   NIV failure

3.96

1.74 to 8.99

0.001

   Invasive MV

2.67

1.32 to 5.39

0.006

Cumulative fluid balance (72 h)

0.005

   < -1.5 L

3.08

1.47 to 6.48

0.003

   -1.5 L to +1.5 L

ref

ref

   > +1.5 L to +5.0 L

1.84

1.11 to 3.04

0.018

   > 5.0 L

2.44

1.39 to 4.28

0.002

Lactate levels (Ln + 0.5)

1.78

1.27 to 2.51

0.001