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Table 2 Factors associated with hospital mortality in a multivariate analysis

From: Clinical outcomes of patients requiring ventilatory support in Brazilian intensive care units: a multicenter, prospective, cohort study

Parameter OR CI 95% P-value
Age 1.03 1.01 to 1.03 < 0.001
SOFA Score excluding respiratory component 1.12 1.05 to 1.19 < 0.001
Charlson comorbidity index    0.002
   0 ref ref  
   1 to 2 1.37 0.92 to 2.04 0.124
   > 2 2.30 1.28 to 3.17 < 0.001
ARDS    0.037
   Absence ARDS ref ref  
   ARDS mild 1.09 0.68 to 1.73 0.721
   ARDS moderate 1.92 1.11 to 3.35 0.02
   ARDS severe 2.12 1.02 to 4.41 0.045
Mechanical ventilation    0.004
   Successful NIV ref ref  
   NIV failure 3.96 1.74 to 8.99 0.001
   Invasive MV 2.67 1.32 to 5.39 0.006
Cumulative fluid balance (72 h)    0.005
   < -1.5 L 3.08 1.47 to 6.48 0.003
   -1.5 L to +1.5 L ref ref  
   > +1.5 L to +5.0 L 1.84 1.11 to 3.04 0.018
   > 5.0 L 2.44 1.39 to 4.28 0.002
Lactate levels (Ln + 0.5) 1.78 1.27 to 2.51 0.001
  1. Abbreviations: ARDS, Acute Respiratory Distress Syndrome; MV, Mechanical ventilation; NIV, Non-invasive ventilation; SOFA, Sequential Organ Failure Assessment Score. Area under receiver operating curve for predicted mortality (95% CI): 0.77 (0.73 to 0.81), P < 0.001. Hosmer-Lemeshow Χ2: 8.535, P = 0.383.