Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care

Table 5 Biomarker levels according study group.

	Cut off	SIRS N= 75	Sepsis N= 87	OR	P	Severe SIRS N= 50	Severe sepsis N= 76	OR	P
PCT	1.0 ng/ml	13/74*	62/87	11.6 (5.5 to 24.8)	< 0.0001	9/49*	56/76	12.4 (5.1 to 30.2)	< 0.0001
PSP	30 ng/ml	13/75	78/87	41.3 (16.6 to 103.0)	< 0.0001	11/50	67/76	26.4 (10.1 to 69.3)	< 0.0001
sCD25	2.5 ng/ml	13/75	72/87	22.9 (10.1 to 51.8)	< 0.0001	11/50	61/76	14.4 (6.0 to 34.7)	< 0.0001
HBP	50 ng/ml	48/75	68/87	2.0 (1.0 to 4.0)	0.06	31/50	59/76	2.1 (1.0 to 4.7)	0.07
IL6	200 ng/ml	24/75	59/87	4.5 (2.3 to 8.7)	< 0.0001	17/50	54/76	4.8 (2.2 to 10.3)	< 0.0001
IL8	80 ng/ml	28/75	68/87	6.0 (3.0 to 12.0)	< 0.0001	21/50	62/76	6.1 (2.7 to 13.7)	< 0.0001
IL1b	1.0 ng/ml	9/75	57/87	13.9 (6.1 to 31.8)	< 0.0001	6/50	49/76	13.3 (5.5 to 35.3)	< 0.0001

Univariate odds ratios (95% confidence intervals) are given for sepsis or severe sepsis using cut-offs derived by ROC analysis. * One patient with severe SIRS did not have PCT measured.

ISSN: 1364-8535