Skip to main content

Table 5 Biomarker levels according study group.

From: Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care

  Cut off SIRS
N= 75
Sepsis
N= 87
OR P Severe SIRS
N= 50
Severe sepsis
N= 76
OR P
PCT 1.0 ng/ml 13/74* 62/87 11.6 (5.5 to 24.8) < 0.0001 9/49* 56/76 12.4 (5.1 to 30.2) < 0.0001
PSP 30 ng/ml 13/75 78/87 41.3 (16.6 to 103.0) < 0.0001 11/50 67/76 26.4 (10.1 to 69.3) < 0.0001
sCD25 2.5 ng/ml 13/75 72/87 22.9 (10.1 to 51.8) < 0.0001 11/50 61/76 14.4 (6.0 to 34.7) < 0.0001
HBP 50 ng/ml 48/75 68/87 2.0 (1.0 to 4.0) 0.06 31/50 59/76 2.1 (1.0 to 4.7) 0.07
IL6 200 ng/ml 24/75 59/87 4.5 (2.3 to 8.7) < 0.0001 17/50 54/76 4.8 (2.2 to 10.3) < 0.0001
IL8 80 ng/ml 28/75 68/87 6.0 (3.0 to 12.0) < 0.0001 21/50 62/76 6.1 (2.7 to 13.7) < 0.0001
IL1b 1.0 ng/ml 9/75 57/87 13.9 (6.1 to 31.8) < 0.0001 6/50 49/76 13.3 (5.5 to 35.3) < 0.0001
  1. Univariate odds ratios (95% confidence intervals) are given for sepsis or severe sepsis using cut-offs derived by ROC analysis. * One patient with severe SIRS did not have PCT measured.