Table 3 Diagnostic performance of biomarkers.
From: Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care
Marker | AUC (95% CI) | Cut off | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|
PCT | 0.84 (0.78 to 0.90) | 1.0 ng/ml | 71% | 82% | 83% | 71% |
PSP | 0.93 (0.89 to 0.97) | 30 ng/ml | 90% | 83% | 86% | 87% |
sCD25 | 0.90 (0.85 to 0.95) | 2.5 ng/ml | 83% | 83% | 85% | 81% |
HBP | 0.60 (0.52 to 0.69) | 50 ng/ml | 78% | 36% | 59% | 59% |
IL6 | 0.81 (0.74 to 0.87) | 200 pg/ml | 68% | 68% | 71% | 65% |
IL8 | 0.78 (0.71 to 0.85) | 80 pg/ml | 78% | 63% | 71% | 71% |
IL1β | 0.76 (0.69 to 0.84) | 1.0 pg/ml | 61% | 88% | 86% | 69% |