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Figure 5 | Critical Care

Figure 5

From: Leukocyte capture and modulation of cell-mediated immunity during human sepsis: an ex vivo study

Figure 5

Effects of extracorporeal circuits on leukocyte surface marker expression, in septic blood. (A, B) Geometric mean of fluorescence intensity of CD 11b, HLA-DR, CD 11a, CD 62L, TACE, and NFkB and positive cells for Annexin V in monocytes and PMN. Data are expressed as % of the uncirculated condition (medians with interquartile ranges). (C) Percentage of CD3+/CD4- and CD3+/CD4+ cells among T-lymphocytes (medians with interquartile ranges). (D) Percentage of positive cells for CD69 among CD3+/CD4- and CD3+/CD4+ cells (medians with interquartile ranges). (E): Geometric mean of fluorescence intensity of CD69 in CD3+/CD4- and CD3+/CD4+ cells (medians with interquartile ranges). *P < .05, **P < .01, ***P < .001 compared with Sham. Annex. V, Annexin V; Mono, monocytes; NFkB, nuclear factor-kappa B; PMN, neutrophils; TACE, tumor necrosis factor-alpha converting enzyme.

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