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Table 4 Pruritus in patients with severe sepsis allocated to HES 130/0

From: Quality of life and pruritus in patients with severe sepsis resuscitated with hydroxyethyl starch long-term follow-up of a randomised trial

 

HES

130/0.42

Ringer's acetate

Relative risk (95%CI)

P value

Primary outcome

    

Pruritus at any time after discharge, n/N (%)

47/96 (49)

38/88 (43)

1.13 (0.83-1.55)

0.43

Secondary outcomes

    

Pruritus in the last 48 hours, n/N (%)

31/95 (33)

24/89 (27)

1.21 (0.77-1.89)

0.40

VAS score, median (IQR)*

4.5 (3.5-5.5)

3.5 (2.0-6.5)

-

0.28

Action taken against pruritus n/N (%)

36/96 (37)

20/88 (23)

1.65 (1.04-2.62)

0.03

   Use of ointment/tablets n/N (%)

36/96 (37)

19/88 (21)

1.74 (1.08-2.79)

0.02

   Consulted GP n/N (%)

11/96 (11)

7/88 (8)

1.26 (0.53-2.99)

0.60

   Consulted dermatologist n/N (%)

2/96 (2)

5/88 (6)

0.37 (0.07-1.84)

0.20

  1. N = number of patients in the treatment group. n = number of cases. *Medians are for those who had pruritus within the last 48 hours. HES, hydroxyethyl starch; VAS, visual analogue scale; IQR, interquartile range, GP, general practitioner.