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Table 2 Characteristics at randomization of patients who responded to at least one of the questionnaires.

From: Quality of life and pruritus in patients with severe sepsis resuscitated with hydroxyethyl starch long-term follow-up of a randomised trial

 

HES 130/0.42

(n= 98)

Ringer's acetate

(n= 92)

Time to follow-up - months

13 (9-17)

14 (10-18)

Age - years

66 (59-74)

66 (58-75)

Male gender - no. (%)

52 (53)

53 (58)

Included at university hospital - no. (%)

35 (36)

36 (39)

Surgery 1 - no. (%)

  

   Emergency

31 (32)

33 (36)

   Elective

7 (7)

17 (18)

Source of ICU admittance - no. (%)

  

   Emergency department

32 (33)

21 (23)

   General ward

40 (41)

39 (42)

   Operating or recovery room

17 (17)

21 (23)

   Other ICU in the same hospital

2 (2)

2 (2)

   Other hospital

7 (7)

9 (10)

Source of sepsis 2 - no. (%)

  

   Lungs

42 (43)

38 (41)

   Abdomen

40 (41)

33 (36)

   Urinary tract

13 (13)

13 (14)

   Soft tissue

9 (9)

14 (15)

   Other

10 (10)

12 (13)

Positive culture from blood or a sterile site - no. (%)

17 (17)

11 (12)

Time from ICU admission to randomization - hours

3 (1-11)

3 (1-14)

SAPS II

48 (36-58)

50 (38-59)

SOFA score 3

7 (5-9)

7 (5-9)

Shock 4 - no. (%)

80 (82)

80 (87)

Acute kidney injury 5 - no. (%)

36 (37)

35 (38)

Mechanical ventilation - no. (%)

44 (45)

54 (59)

Comorbidities

  

   Diabetes mellitus - no. (%)

12 (12)

16 (17)

   Arterial hypertension - no. (%)

42 (43)

39 (42)

   Chronic renal disease6 - no. (%)

9 (10)

14 (17)

   Hematological malignancy - no. (%)

6 (6)

9 (10)

Previous admission for - no. (%)

  

   Heart failure or myocardial infarction

10 (10)

12 (13)

   Stroke

7 (7)

6 (7)

   Asthma or COPD

12 (12)

12 (13)

Any ventilation in the ICU, n (%)

71 (72)

72 (78)

Days in ventilator if treated, median (IQR)

6 (3-14)

5 (3-12)

Any renal replacement therapy dialysis in the ICU, n (%)

18 (18)

15 (16)

Days in renal replacement therapy if treated, median (IQR)

7 (3-22)

10 (6-22)

Days in ICU, median (IQR)

6 (3-14)

8 (4-14)

Days in hospital in the 90 days follow-up period, median (IQR)

32 (20-50)

30 (20-53)

  1. 1Numbers are for patients who underwent surgery during the index hospitalization, but before randomization. 2Some patients had more than one source of infection. The 'other' category included sepsis from a vascular catheter-related infection, meningitis, or endocarditis, as well as sepsis from unknown sources. 3The SOFA scoring was modified because cerebral failure was not assessed. 4Shock at randomization was defined as a mean arterial pressure of less than 70 mm Hg, the need for ongoing treatment with vasopressor or inotropic agents, or a plasma lactate level of more than 4.0 mmol per liter in the hour before randomization. 5Acute kidney injury was defined as a renal SOFA score of 2 or higher (plasma creatinine level > 170 μmol/l (1.9 mg/dl) or urinary output < 500 ml/d). 6Chronic renal disease was defined as a preadmission plasma creatinine > 100 μmol/l (1.2 mg/dl). HES, hydroxyethyl starch; SAPS, simplified acute physiology score; SOFA, sequential organ failure assessment, COPD, chronic obstructive pulmonary disease; IQR, interquartile range.