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Figure 1 | Critical Care

Figure 1

From: The elusive task of biomarkers of renal injury

Figure 1

Serum/urine neutrophil-gelatinase associated lipocalin increase might outweigh renal function biomarkers for prediction of adverse outcome. Several lines of evidence suggest that a rise of serum or urine level of neutrophil-gelatinase associated lipocalin (NGAL) might outweigh biomarkers of renal function for prediction of adverse outcome (that is, mortality). Further prospective studies should confirm these findings. Dashed lines enclose potential effectors linking biomarkers of renal function (for example, serum creatinine) and renal injury (for example, NGAL) to poor outcome. These factors can affect the serum level of these biomarkers (+) but can also influence outcome (-). Further research should explore the significance of these associations and will unveil the specificity of the biomarkers toward renal injury.

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